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Cellosaurus Detroit 532 (CVCL_2430)

Cell line name Detroit 532
Synonyms Detroit-532; Detroit532; Det 532; DS-Fibr
Accession CVCL_2430
Resource Identification Initiative To cite this cell line use: Detroit 532 (RRID:CVCL_2430)
Comments Population: Caucasian.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
Cell type: Fibroblast of foreskin; CL=CL_1001608.
Disease Down syndrome (NCIt: C2993)
Down syndrome (ORDO: Orphanet_870)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C252 (ATCC-DYP0730)CVCL_ZA02 (DS1-iPS)CVCL_ZA03 (DS2-iPS)
CVCL_ZA04 (euDS-iPS)CVCL_D0KA (NSI003-A)CVCL_D0KB (NSI003-B)
Sex of cell Male
Age at sampling 2M
Category Finite cell line
STR profile Source(s): ATCC; ECACC; IZSLER; JCRB; PubMed=17254797

Markers:
AmelogeninX,Y
CSF1PO11 (PubMed=17254797)
12 (ATCC; ECACC; IZSLER; JCRB)
D2S133822,25
D3S135817,18
D5S8189,12
D7S8208
D8S117912
D13S31711,13
D16S53910,13
D18S5112,13
D19S43313,14
D21S1130,31 (PubMed=17254797)
30,31.2 (ATCC; IZSLER)
FGA20,24
Penta D8,9,13
Penta E13,16
TH017,9
TPOX8
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=5668122; DOI=10.3181/00379727-128-33119
Peterson W.D. Jr., Stulberg C.S., Swanborg N.K., Robinson A.R.
Glucose-6-phosphate dehydrogenase isoenzymes in human cell cultures determined by sucrose-agar gel and cellulose acetate zymograms.
Proc. Soc. Exp. Biol. Med. 128:772-776(1968)

DOI=10.1007/BF02618370
Stulberg C.S., Coriell L.L., Kniazeff A.J., Shannon J.E.
The animal cell culture collection.
In Vitro 5:1-16(1970)

PubMed=6988327; DOI=10.1007/BF02831503
O'Brien S.J., Shannon J.E., Gail M.H.
A molecular approach to the identification and individualization of human and animal cells in culture: isozyme and allozyme genetic signatures.
In Vitro 16:119-135(1980)

PubMed=7471105
Weichselbaum R.R., Nove J., Little J.B.
X-ray sensitivity of fifty-three human diploid fibroblast cell strains from patients with characterized genetic disorders.
Cancer Res. 40:920-925(1980)

PubMed=7329430; DOI=10.1016/0027-5107(81)90059-2
Nove J., Nichols W.W., Weichselbaum R.R., Little J.B.
Abnormalities of human chromosome 13 and in vitro radiosensitivity; a study of 19 fibroblast strains.
Mutat. Res. 84:157-167(1981)

PubMed=17254797; DOI=10.1016/j.biologicals.2006.10.001
Azari S., Ahmadi N., Tehrani M.J., Shokri F.
Profiling and authentication of human cell lines using short tandem repeat (STR) loci: report from the National Cell Bank of Iran.
Biologicals 35:195-202(2007)

PubMed=23225669; DOI=10.1002/stem.1297
Briggs J.A., Sun J., Shepherd J., Ovchinnikov D.A., Chung T.-L., Nayler S.P., Kao L.-P., Morrow C.A., Thakar N.Y., Soo S.-Y., Peura T.T., Grimmond S.M., Wolvetang E.J.
Integration-free induced pluripotent stem cells model genetic and neural developmental features of Down syndrome etiology.
Stem Cells 31:467-478(2013)

Cross-references
Cell line collections (Providers) ATCC; CCL-54
ECACC; 87032602
IZSLER; BS CL 30
JCRB; JCRB9044
NCBI_Iran; C438
Cell line databases/resources CLO; CLO_0002747
CLDB; cl1026
CLDB; cl1027
Biological sample resources BioSample; SAMN01821550
BioSample; SAMN01821678
BioSample; SAMN03471281
Encyclopedic resources Wikidata; Q54830992
Gene expression databases GEO; GSM1053958
GEO; GSM1053959
GEO; GSM1053960
GEO; GSM1053982
GEO; GSM1053983
GEO; GSM1053984
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number21