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Cellosaurus H357 (CVCL_2462)

[Text version]

Cell line name H357
Accession CVCL_2462
Resource Identification Initiative To cite this cell line use: H357 (RRID:CVCL_2462)
Comments Derived from sampling site: Oral cavity; tongue.
Sequence variations Mutation; HGNC; 5173; HRAS; Simple; p.Gly13Ser (c.37G>A); ClinVar=VCV000376323; Zygosity=Unspecified (DepMap).
Mutation; HGNC; 11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Homozygous (PubMed=7633286).
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_JY67 (H357-V3)
Sex of cell Male
Age at sampling 74Y
Category Cancer cell line
STR profile Source(s): DepMap

Markers:
AmelogeninX,Y
CSF1PO11,13
D3S135817,18
D5S81812,14
D7S82011
D8S117913
D13S31712,13
D16S53911,12
D18S5114,17
D21S1129,31.2
FGA23,26
Penta D6,12
Penta E11,13
TH016,9
TPOX8,11
vWA17,19

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Publications

PubMed=1692339; DOI=10.1002/path.1711600313
Prime S.S., Nixon S.V., Crane I.J., Stone A., Matthews J.B., Maitland N.J., Remnant L., Powell S.K., Game S.M., Scully C.
The behaviour of human oral squamous cell carcinoma in cell culture.
J. Pathol. 160:259-269(1990)

PubMed=7633286; DOI=10.1016/0964-1955(94)00030-8
Yeudall W.A., Paterson I.C., Patel V., Prime S.S.
Presence of human papillomavirus sequences in tumour-derived human oral keratinocytes expressing mutant p53.
Eur. J. Cancer B Oral Oncol. 31:136-143(1995)

PubMed=8552382
Jones J., Sugiyama M., Speight P.M., Watt F.M.
Restoration of alpha V beta 5 integrin expression in neoplastic keratinocytes results in increased capacity for terminal differentiation and suppression of anchorage-independent growth.
Oncogene 12:119-126(1996)

PubMed=17944752; DOI=10.1111/j.1600-0714.2007.00617.x
Harper L.J., Piper K., Common J., Fortune F., Mackenzie I.C.
Stem cell patterns in cell lines derived from head and neck squamous cell carcinoma.
J. Oral Pathol. Med. 36:594-603(2007)

PubMed=20426848; DOI=10.1186/1471-2407-10-166
Harper L.J., Costea D.E., Gammon L., Fazil B., Biddle A., Mackenzie I.C.
Normal and malignant epithelial cells with stem-like properties have an extended G2 cell cycle phase that is associated with apoptotic resistance.
BMC Cancer 10:166.1-166.16(2010)

PubMed=27846777; DOI=10.1089/ten.TEC.2016.0310
Jennings L.R., Colley H.E., Ong J., Panagakos F., Masters J.G., Trivedi H.M., Murdoch C., Whawell S.
Development and characterization of in vitro human oral mucosal equivalents derived from immortalized oral keratinocytes.
Tissue Eng. Part C Methods 22:1108-1117(2016)

Cross-references
Cell line collections ECACC; 06092004
Ximbio; 153422
Cell line databases/resources DepMap; ACH-001509
Other Wikidata; Q54872075
Polymorphism and mutation databases Cosmic; 716676
Cosmic; 916370
Cosmic; 928237
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number14