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Cellosaurus H376 (CVCL_2463)

[Text version]

Cell line name H376
Accession CVCL_2463
Resource Identification Initiative To cite this cell line use: H376 (RRID:CVCL_2463)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Derived from sampling site: Oral cavity; floor of mouth.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Gly266Ter (c.796G>T); ClinVar=VCV000954591; Zygosity=Homozygous (PubMed=7633286; DepMap).
Disease Floor of mouth squamous cell carcinoma (NCIt: C4041)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 40Y
Category Cancer cell line
STR profile Source(s): DepMap; ECACC

Markers:
AmelogeninX
CSF1PO10,11
D3S135815,17
D5S81810,12
D7S8208,10
D8S117913,17
D13S3178,11
D16S53911
D18S5112,14
D21S1129,30
FGA19,22
Penta D12,14
Penta E7,10
TH016,9
TPOX8
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=1692339; DOI=10.1002/path.1711600313
Prime S.S., Nixon S.V., Crane I.J., Stone A., Matthews J.B., Maitland N.J., Remnant L., Powell S.K., Game S.M., Scully C.
The behaviour of human oral squamous cell carcinoma in cell culture.
J. Pathol. 160:259-269(1990)

PubMed=7633286; DOI=10.1016/0964-1955(94)00030-8
Yeudall W.A., Paterson I.C., Patel V., Prime S.S.
Presence of human papillomavirus sequences in tumour-derived human oral keratinocytes expressing mutant p53.
Eur. J. Cancer B Oral Oncol. 31:136-143(1995)

Cross-references
Cell line collections CancerTools; 153423
ECACC; 06092005
Ximbio; 153423
Cell line databases/resources Cell_Model_Passport; SIDM01857
DepMap; ACH-001510
Encyclopedic resources Wikidata; Q54872114
Polymorphism and mutation databases Cosmic; 716677
Cosmic; 916371
Cosmic; 928238
Entry history
Entry creation04-Apr-2012
Last entry update23-Jun-2022
Version number14