Home  |  Contact

Cellosaurus H69V (CVCL_2466)

[Text version]
Cell line name H69V
Synonyms H69v; MOG-H69V
Accession CVCL_2466
Secondary accession CVCL_S829
Resource Identification Initiative To cite this cell line use: H69V (RRID:CVCL_2466)
Comments Population: Caucasian.
Doubling time: 34.0 hours (PubMed=1662924).
Omics: SNP array analysis.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Gly106_Arg108del (c.317_325delGGCAACCGT); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9884; RB1; Simple; p.Glu748Ter (c.2242G>T); ClinVar=VCV000013078; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Glu171Ter (c.511G>T); ClinVar=VCV000634771; Zygosity=Homozygous (from parent cell line).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1579 (NCI-H69)
Sex of cell Male
Age at sampling 55Y
Category Cancer cell line
STR profile Source(s): ECACC

Markers:
AmelogeninX,Y
CSF1PO10,12
D5S81811,13
D7S8209
D13S31712
D16S53911
TH018,9
TPOX10
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=1662924
Khan M.Z., Freshney R.I., Murray A.M.B., Merry S., Plumb J.A., McNicol A.M.
Identification and characterisation in vitro of cells with a non-SCLC cell-like phenotype derived from a continuous SCLC cell line.
Anticancer Res. 11:1687-1695(1991)

PubMed=8712684
Khan M.Z., McNicol A.M., Freshney R.I.
Tumorigenicity, invasion and metastasis of the small cell lung cancer cell line NCI-H69 and two derivative lines MOG-H69V and MOG-H69VZ.
Anticancer Res. 16:1659-1669(1996)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cross-references
Cell line collections (Providers) ECACC; 91091803
Cell line databases/resources CLO; CLO_0003611
CLDB; cl1554
cancercelllines; CVCL_2466
LINCS_LDP; LCL-1875
Encyclopedic resources Wikidata; Q54872208
Gene expression databases GEO; GSM827449
Polymorphism and mutation databases Progenetix; CVCL_2466
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number24