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Cellosaurus HCA7 colony 29 (CVCL_2474)

[Text version]
Cell line name HCA7 colony 29
Synonyms HCA-7 Colony 29; HCA-7 Colony29; Col 29
Accession CVCL_2474
Resource Identification Initiative To cite this cell line use: HCA7 colony 29 (RRID:CVCL_2474)
Comments Characteristics: Useful for studying the role of PTGS2 (Cox-2) in cancer cell biology and the investigation of colorectal epithelial cell polarity.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0289 (HCA7)
Sex of cell Female
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): ECACC

Markers:
AmelogeninX
CSF1PO11,14
D5S8188,12
D7S82011,12
D13S3179
D16S53910,11
TH016,7
TPOX8,10
vWA14,16

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Publications

PubMed=8410493; DOI=10.1002/path.1711700407
Marsh K.A., Stamp G.W.H., Kirkland S.C.
Isolation and characterization of multiple cell types from a single human colonic carcinoma: tumourigenicity of these cell types in a xenograft system.
J. Pathol. 170:441-450(1993)

PubMed=9012840; DOI=10.1073/pnas.94.2.657
Coffey R.J., Hawkey C.J., Damstrup L., Graves-Deal R., Daniel V.C., Dempsey P.J., Chinery R., Kirkland S.C., DuBois R.N., Jetton T.L., Morrow J.D.
Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells.
Proc. Natl. Acad. Sci. U.S.A. 94:657-662(1997)

Cross-references
Cell line collections (Providers) ECACC; 02091238
Ximbio; 152459 - Discontinued
Encyclopedic resources Wikidata; Q54881498
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number13