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Cellosaurus HL-60 clone 15-12 (CVCL_2494)

[Text version]
Cell line name HL-60 clone 15-12
Synonyms HL60 15-12
Accession CVCL_2494
Resource Identification Initiative To cite this cell line use: HL-60 clone 15-12 (RRID:CVCL_2494)
Comments Population: Caucasian.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene deletion; HGNC; 11998; TP53; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2493 (HL-60 clone 15)
Sex of cell Female
Age at sampling 36Y
Category Cancer cell line
Publications

PubMed=3165665; DOI=10.1038/bjc.1988.128
Bunce C.M., Lord J.M., Wong A.K.-Y., Brown G.
Near neighbour analysis of variant cell lines derived from the promyeloid cell line HL60.
Br. J. Cancer 57:559-563(1988)

Cross-references
Cell line collections (Providers) ECACC; 88120805
Cell line databases/resources CLO; CLO_0003776
CLDB; cl1694
cancercelllines; CVCL_2494
Encyclopedic resources Wikidata; Q54889799
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number21