ID   HL-60 clone 15-12
AC   CVCL_2494
SY   HL60 15-12
DR   CLO; CLO_0003776
DR   CLDB; cl1694
DR   ECACC; 88120805
DR   Wikidata; Q54889799
RX   PubMed=3165665;
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; 11998; TP53; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Derived from sampling site: Peripheral blood.
DI   NCIt; C9154; Adult acute myeloid leukemia
DI   ORDO; Orphanet_519; Acute myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_2493 ! HL-60 clone 15
SX   Female
AG   36Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 23-09-21; Version: 18
//
RX   PubMed=3165665; DOI=10.1038/bjc.1988.128;
RA   Bunce C.M., Lord J.M., Wong A.K.-Y., Brown G.;
RT   "Near neighbour analysis of variant cell lines derived from the
RT   promyeloid cell line HL60.";
RL   Br. J. Cancer 57:559-563(1988).
//