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Cellosaurus HRA-19a1.1 (CVCL_2509)

[Text version]
Cell line name HRA-19a1.1
Accession CVCL_2509
Resource Identification Initiative To cite this cell line use: HRA-19a1.1 (RRID:CVCL_2509)
Comments Derived from site: In situ; Rectum; UBERON=UBERON_0001052.
Sequence variations
  • Mutation; HGNC; 583; APC; Simple; p.Arg405Ter (c.1213C>T); ClinVar=VCV000127275; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 583; APC; Simple; p.Arg1450Ter (c.4348C>T); ClinVar=VCV000194585; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 914; B2M; Simple; p.Ser16Alafs*27 (c.42_45delTCTT); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
Disease Rectal adenocarcinoma (NCIt: C9383)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2508 (HRA-19)
Children:
CVCL_2512 (HRA-19a1.1 Alpha2 B)CVCL_2513 (HRA-19a1.1 Alpha2 F)CVCL_2510 (HRA-19a1.1 Alpha2Alpha1 B)
CVCL_2511 (HRA-19a1.1 Alpha2Alpha1 E)
Sex of cell Male
Age at sampling 66Y
Category Cancer cell line
STR profile Source(s): ECACC

Markers:
AmelogeninX,Y
CSF1PO12
D5S81811
D7S8209,12
D13S31712
D16S53911
TH018
TPOX11
vWA16

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Publications

PubMed=2449944; DOI=10.1002/1097-0142(19880401)61:7<1359::AID-CNCR2820610714>3.0.CO;2-0
Kirkland S.C.
Clonal origin of columnar, mucous, and endocrine cell lineages in human colorectal epithelium.
Cancer 61:1359-1363(1988)

Cross-references
Cell line collections (Providers) ECACC; 09071517
Ximbio; 152466 - Discontinued
Cell line databases/resources cancercelllines; CVCL_2509
Encyclopedic resources Wikidata; Q54895215
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number18