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Cellosaurus JIM1 (CVCL_2532)

[Text version]

Cell line name JIM1
Synonyms JIM-1
Accession CVCL_2532
Resource Identification Initiative To cite this cell line use: JIM1 (RRID:CVCL_2532)
Comments Derived from sampling site: Pleural effusion.
Sequence variations Gene fusion; HGNC; 5865; IGLJ3 + HGNC; 5905; IGLV3-21; Name(s)=IGLV3-21-IGLJ3 (CelloPub=CLPUB00604).
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_2533 ! JIM3
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Web pages https://www.keatslab.org/myeloma-cell-lines/hmcl-characteristics
Publications

PubMed=1943229
Hamilton M.S., Barker H.F., Ball J., Drew M., Abbot S.D., Franklin I.M.
Normal and neoplastic human plasma cells express bcl-2 antigen.
Leukemia 5:768-771(1991)

PubMed=10087940; DOI=10.1016/S0165-4608(98)00157-5
Kuipers J., Vaandrager J.W., Weghuis D.O., Pearson P.L., Scheres J., Lokhorst H.M., Clevers H., Bast B.J.E.G.
Fluorescence in situ hybridization analysis shows the frequent occurrence of 14q32.3 rearrangements with involvement of immunoglobulin switch regions in myeloma cell lines.
Cancer Genet. Cytogenet. 109:99-107(1999)

DOI=10.1007/0-306-46877-8_4
Jernberg-Wiklund H., Nilsson K.
Multiple myeloma cell lines.
(In) Human cell culture. Vol. 3. Cancer Cell Lines part 3; Masters J.R.W., Palsson B.O. (eds.); pp.81-155; Kluwer Academic Publishers; New York (2000)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Drexler H.G., Matsuo Y.
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

PubMed=11021758; DOI=10.1038/sj.leu.2401891
Majka M., Rozmyslowicz T., Honczarenko M., Ratajczak J., Wasik M.A., Gaulton G.N., Ratajczak M.Z.
Biological significance of the expression of HIV-related chemokine coreceptors (CCR5 and CXCR4) and their ligands by human hematopoietic cell lines.
Leukemia 14:1821-1832(2000)

CLPUB00604
Chow S.
Targeted capture and sequencing of immunoglobulin rearrangements in multiple myeloma to enable detection of minimal residual disease.
Thesis MSc (2017), University of Toronto, Canada

Cross-references
Cell line collections ECACC; 10032303
Ximbio; 151449
Other Wikidata; Q54898924
Polymorphism and mutation databases Cosmic; 888015
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number15