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Cellosaurus K1 (CVCL_2537)

[Text version]

Cell line name K1
Accession CVCL_2537
Resource Identification Initiative To cite this cell line use: K1 (RRID:CVCL_2537)
Comments Problematic cell line: Contaminated. Shown to be a GLAG-66 derivative (PubMed=19087340; PubMed=20143388).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00218.
Doubling time: 24 hours (PubMed=9054892).
Disease Thyroid gland papillary carcinoma (NCIt: C4035)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9918 (GLAG-66)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): ECACC; PubMed=18713817; PubMed=23162534

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133820,23
D3S135818
D5S81810,11
D7S82011
D8S117915
D13S31711,14
D16S53911,12
D18S5118
D21S1130,31.2
FGA21,24
TH016,9
TPOX8
vWA17,18

Run an STR similarity search on this cell line
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations_v9_distribution.xlsx
Publications

PubMed=9054892; DOI=10.1016/S0360-3016(96)00449-X
Challeton C., Branea F., Schlumberger M., Gaillard N., de Vathaire F., Badie C., Antonini P., Parmentier C.
Characterization and radiosensitivity at high or low dose rate of four cell lines derived from human thyroid tumors.
Int. J. Radiat. Oncol. Biol. Phys. 37:163-169(1997)

PubMed=17725429; DOI=10.1089/thy.2007.0097
Meireles A.M., Preto A., Rocha A.S., Rebocho A.P., Maximo V., Pereira-Castro I., Moreira S., Feijao T., Botelho T., Marques R., Trovisco V., Cirnes L., Alves C., Velho S., Soares P., Sobrinho-Simoes M.
Molecular and genotypic characterization of human thyroid follicular cell carcinoma-derived cell lines.
Thyroid 17:707-715(2007)

PubMed=18713817; DOI=10.1210/jc.2008-1102
Schweppe R.E., Klopper J.P., Korch C., Pugazhenthi U., Benezra M., Knauf J.A., Fagin J.A., Marlow L.A., Copland J.A., Smallridge R.C., Haugen B.R.
Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification.
J. Clin. Endocrinol. Metab. 93:4331-4341(2008)

PubMed=19087340; DOI=10.1186/1471-2407-8-371
Ribeiro F.R., Meireles A.M., Rocha A.S., Teixeira M.R.
Conventional and molecular cytogenetics of human non-medullary thyroid carcinoma: characterization of eight cell line models and review of the literature on clinical samples.
BMC Cancer 8:371-371(2008)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=22087789; DOI=10.1186/1755-8166-4-26
Maric I., Viaggi S., Caria P., Frau D.V., Degan P., Vanni R.
Centrosomal and mitotic abnormalities in cell lines derived from papillary thyroid cancer harboring specific gene alterations.
Mol. Cytogenet. 4:26-26(2011)

PubMed=23162534; DOI=10.3389/fendo.2012.00133
Saiselet M., Floor S., Tarabichi M., Dom G., Hebrant A., van Staveren W.C.G., Maenhaut C.
Thyroid cancer cell lines: an overview.
Front. Endocrinol. 3:133-133(2012)

PubMed=25675381; DOI=10.1210/jc.2014-2764
von Roemeling C.A., Marlow L.A., Pinkerton A.B., Crist A., Miller J., Tun H.W., Smallridge R.C., Copland J.A.
Aberrant lipid metabolism in anaplastic thyroid carcinoma reveals stearoyl CoA desaturase 1 as a novel therapeutic target.
J. Clin. Endocrinol. Metab. 100:E697-E709(2015)

Cross-references
Cell line collections AddexBio; C0025003/51
BCRJ; 0292
ECACC; 92030501
Cell line databases/resources CLDB; cl2988
Ontologies CLO; CLO_0007052
Biological sample resources BioSample; SAMN03151643
Other Wikidata; Q54899238
Polymorphism and mutation databases Cosmic; 928833
Cosmic; 1084280
Cosmic; 1132597
Cosmic; 1162845
Cosmic; 1239966
Cosmic; 1280046
Cosmic; 1507368
Cosmic; 1533546
Cosmic; 1536121
Cosmic; 1889001
Cosmic; 2036691
Cosmic; 2319846
Cosmic; 2613254