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Cellosaurus Karpas-25 (CVCL_2540)

[Text version]
Cell line name Karpas-25
Synonyms KARPAS-25; Karpas 25; KARPAS 25; Karpas25
Accession CVCL_2540
Resource Identification Initiative To cite this cell line use: Karpas-25 (RRID:CVCL_2540)
Comments Doubling time: ~30 hours (ECACC=06072601; Ximbio=152420).
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 27Y
Category Cancer cell line
Web pages https://www.keatslab.org/myeloma-cell-lines/hmcl-characteristics
Publications

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Drexler H.G., Matsuo Y.
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

PubMed=15621787; DOI=10.1080/10428190400002244
Karpas A., Harder L., Czepulkowski B.H., Bloxham D., Saward R., Dremucheva A., Siebert R.
Studies of four new human myeloma cell lines.
Leuk. Lymphoma 46:101-112(2005)

CLPUB00604
Chow S.
Targeted capture and sequencing of immunoglobulin rearrangements in multiple myeloma to enable detection of minimal residual disease.
Thesis MSc (2017), University of Toronto, Canada

PubMed=32123307; DOI=10.1038/s41375-020-0785-1
Sarin V., Yu K., Ferguson I.D., Gugliemini O., Nix M.A., Hann B., Sirota M., Wiita A.P.
Evaluating the efficacy of multiple myeloma cell lines as models for patient tumors via transcriptomic correlation analysis.
Leukemia 34:2754-2765(2020)

Cross-references
Cell line collections (Providers) ECACC; 06072601
Ximbio; 152420
Encyclopedic resources Wikidata; Q54899494
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number15