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Cellosaurus XP6BR LCL (CVCL_2558)

[Text version]
Cell line name XP6BR LCL
Synonyms Xeroderma Pigmentosum 6 BRighton LCL; LB253; 253
Accession CVCL_2558
Resource Identification Initiative To cite this cell line use: XP6BR LCL (RRID:CVCL_2558)
Comments Population: Caucasian.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; 12816; XPC; Simple; p.Thr808Valfs*48 (c.2421_2604del184); Zygosity=Heterozygous (from autologous cell line XP6BR).
Disease Xeroderma pigmentosum, complementation group C (NCIt: C114770)
Xeroderma pigmentosum (ORDO: Orphanet_910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_ZN51 ! XP6BR
Sex of cell Male
Age at sampling 67Y
Category Transformed cell line
STR profile Source(s): ECACC

Markers:
AmelogeninX,Y
CSF1PO10,12
D5S81811,12
D7S8208,12
D13S31711,12
D16S5399,13
TH016,9.3
TPOX8
vWA17,19

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Publications

PubMed=1372096; DOI=10.1016/0921-8777(92)90074-d
Arlett C.F., Harcourt S.A., Cole J., Green M.H.L., Anstey A.V.
A comparison of the response of unstimulated and stimulated T-lymphocytes and fibroblasts from normal, xeroderma pigmentosum and trichothiodystrophy donors to the lethal action of UV-C.
Mutat. Res. 273:127-135(1992)

Cross-references
Cell line collections (Providers) ECACC; 98062330
Encyclopedic resources Wikidata; Q54902053
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number13