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Cellosaurus LUDLU-1 (CVCL_2582)

Cell line name LUDLU-1
Synonyms Ludlu-1; LUDLU 1; LUDLU1
Accession CVCL_2582
Resource Identification Initiative To cite this cell line use: LUDLU-1 (RRID:CVCL_2582)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Omics: Deep RNAseq analysis.
Omics: Genome sequenced.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Squamous cell lung carcinoma (NCIt: C3493)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_2296 ! AGLCL [Human 1989]
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
STR profile Source(s): ECACC; PubMed=25877200

Penta D10
Penta E12,19

PubMed=2577272; DOI=10.1002/gcc.2870010115
Rabbitts P.H., Douglas J., Daly M., Sundaresan V., Fox B., Haselton P., Wells F., Albertson D., Waters J., Bergh J.
Frequency and extent of allelic loss in the short arm of chromosome 3 in nonsmall-cell lung cancer.
Genes Chromosomes Cancer 1:95-105(1989)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=23226101; DOI=10.1593/neo.121380
Stead L.F., Berri S., Wood H.M., Egan P., Conway C., Daly C., Papagiannopoulos K., Rabbitts P.H.
The transcriptional consequences of somatic amplifications, deletions, and rearrangements in a human lung squamous cell carcinoma.
Neoplasia 14:1075-1086(2012)

PubMed=24002593; DOI=10.1038/bjc.2013.452
Wu D., Pang Y., Wilkerson M.D., Wang D., Hammerman P.S., Liu J.S.
Gene-expression data integration to squamous cell lung cancer subtypes reveals drug sensitivity.
Br. J. Cancer 109:1599-1608(2013)

PubMed=24244370; DOI=10.1371/journal.pone.0078823
Stead L.F., Egan P., Devery A., Conway C., Daly C., Berri S., Wood H.M., Belvedere O., Papagiannopoulos K., Ryan A., Rabbitts P.H.
An integrated inspection of the somatic mutations in a lung squamous cell carcinoma using next-generation sequencing.
PLoS ONE 8:E78823-E78823(2013)

Cell line collections ECACC; 92012463
Cell line databases/resources CLDB; cl3269
Ontologies CLO; CLO_0007417
Biological sample resources BioSample; SAMN03473041
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM827451
GEO; GSM887284
GEO; GSM888359
GEO; GSM1374639
Other Wikidata; Q54903257
Polymorphism and mutation databases Cosmic; 753591
Cosmic; 2060536