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Cellosaurus LUDLU-1 (CVCL_2582)

[Text version]

Cell line name LUDLU-1
Synonyms Ludlu-1; LUDLU 1; LUDLU1
Accession CVCL_2582
Resource Identification Initiative To cite this cell line use: LUDLU-1 (RRID:CVCL_2582)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Omics: Deep RNAseq analysis.
Omics: Genome sequenced.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.82
Native American0.66
East Asian, North3.82
East Asian, South0
South Asian0
European, North56.05
European, South37.65
Disease Squamous cell lung carcinoma (NCIt: C3493)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_2296 ! AGLCL [Human 1989]
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
STR profile Source(s): ECACC; PubMed=25877200

Markers:
AmelogeninX
CSF1PO11
D3S135816,18
D5S81812
D7S82010,12
D8S11798,15
D13S31712
D16S53913,14
D18S5118
D21S1128
FGA25
Penta D10
Penta E12,19
TH016
TPOX8,11
vWA17,19

Run an STR similarity search on this cell line
Publications

PubMed=2577272; DOI=10.1002/gcc.2870010115
Rabbitts P.H., Douglas J., Daly M., Sundaresan V., Fox B., Haselton P., Wells F., Albertson D., Waters J., Bergh J.
Frequency and extent of allelic loss in the short arm of chromosome 3 in nonsmall-cell lung cancer.
Genes Chromosomes Cancer 1:95-105(1989)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=23226101; DOI=10.1593/neo.121380
Stead L.F., Berri S., Wood H.M., Egan P., Conway C., Daly C., Papagiannopoulos K., Rabbitts P.H.
The transcriptional consequences of somatic amplifications, deletions, and rearrangements in a human lung squamous cell carcinoma.
Neoplasia 14:1075-1086(2012)

PubMed=24002593; DOI=10.1038/bjc.2013.452
Wu D., Pang Y., Wilkerson M.D., Wang D., Hammerman P.S., Liu J.S.
Gene-expression data integration to squamous cell lung cancer subtypes reveals drug sensitivity.
Br. J. Cancer 109:1599-1608(2013)

PubMed=24244370; DOI=10.1371/journal.pone.0078823
Stead L.F., Egan P., Devery A., Conway C., Daly C., Berri S., Wood H.M., Belvedere O., Papagiannopoulos K., Ryan A., Rabbitts P.H.
An integrated inspection of the somatic mutations in a lung squamous cell carcinoma using next-generation sequencing.
PLoS ONE 8:E78823-E78823(2013)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections ECACC; 92012463
Cell line databases/resources CLDB; cl3269
CCLE; LUDLU1_LUNG
LINCS_LDP; LCL-1589
Ontologies CLO; CLO_0007417
Biological sample resources BioSample; SAMN03473041
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM827451
GEO; GSM887284
GEO; GSM888359
GEO; GSM1374639
Other Wikidata; Q54903257
Polymorphism and mutation databases Cosmic; 753591
Cosmic; 2060536
Entry history
Entry creation04-Apr-2012
Last entry updated24-May-2019
Version number19