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Cellosaurus MM383 (CVCL_2606)

[Text version]
Cell line name MM383
Synonyms MM 383
Accession CVCL_2606
Resource Identification Initiative To cite this cell line use: MM383 (RRID:CVCL_2606)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=15048078; DepMap).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): CBA; DepMap

Markers:
AmelogeninX,Y
CSF1PO11
D2S133816,19
D3S135817
D5S81811,12
D7S82010,11
D8S117913,14
D13S3178,12
D16S5399,12
D18S5123
D19S43315.2
D21S1129,31
FGA24
Penta D9,14
Penta E11
TH016
TPOX8,11
vWA17,18

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Publications

PubMed=3756862
Maynard K., Parsons P.G.
Cross-sensitivity of methylating agents, hydroxyurea, and methotrexate in human tumor cells of the Mer- phenotype.
Cancer Res. 46:5009-5013(1986)

PubMed=9354451
Castellano M., Pollock P.M., Walters M.K., Sparrow L.E., Down L.M., Gabrielli B.G., Parsons P.G., Hayward N.K.
CDKN2A/p16 is inactivated in most melanoma cell lines.
Cancer Res. 57:4868-4875(1997)

PubMed=10070891; DOI=10.1038/sj.bjc.6690147
Zerp S.F., van Elsas A., Peltenburg L.T.C., Schrier P.I.
p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis.
Br. J. Cancer 79:921-926(1999)

PubMed=15048078; DOI=10.1038/sj.onc.1207563
Pavey S., Johansson P., Packer L., Taylor J., Stark M.S., Pollock P.M., Walker G.J., Boyle G.M., Harper U., Cozzi S.-J., Hansen K., Yudt L., Schmidt C., Hersey P., Ellem K.A.O., O'Rourke M.G.E., Parsons P.G., Meltzer P.S., Ringner M., Hayward N.K.
Microarray expression profiling in melanoma reveals a BRAF mutation signature.
Oncogene 23:4060-4067(2004)

PubMed=17516929; DOI=10.1111/j.1600-0749.2007.00375.x
Johansson P., Pavey S., Hayward N.K.
Confirmation of a BRAF mutation-associated gene expression signature in melanoma.
Pigment Cell Res. 20:216-221(2007)

Cross-references
Cell line collections (Providers) CBA; CBA-1350
ECACC; 10092317
Cell line databases/resources cancercelllines; CVCL_2606
Cell_Model_Passport; SIDM01362
DepMap; ACH-001567
Biological sample resources BioSample; SAMN07624427
Encyclopedic resources Wikidata; Q54906117
Gene expression databases GEO; GSM170843
Polymorphism and mutation databases Cosmic; 889019
Cosmic; 928734
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number22