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Cellosaurus MM386 (CVCL_2607)

[Text version]

Cell line name MM386
Synonyms MM 386
Accession CVCL_2607
Resource Identification Initiative To cite this cell line use: MM386 (RRID:CVCL_2607)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Omics: CNV analysis.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations
Disease Melanoma (NCIt: C3224)
Derived from metastatic site: Lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): CBA; DepMap

Markers:
AmelogeninX,Y
CSF1PO12,14
D2S133826
D3S135815
D5S81811,13
D7S8208,9
D8S117913
D13S3178,12
D16S53911
D18S5112
D19S43314
D21S1130,32
FGA20,22
Penta D9,12
Penta E11,12
TH016,8
TPOX8,9
vWA16,19

Run an STR similarity search on this cell line
Publications

PubMed=9354451
Castellano M., Pollock P.M., Walters M.K., Sparrow L.E., Down L.M., Gabrielli B.G., Parsons P.G., Hayward N.K.
CDKN2A/p16 is inactivated in most melanoma cell lines.
Cancer Res. 57:4868-4875(1997)

PubMed=10070891; DOI=10.1038/sj.bjc.6690147
Zerp S.F., van Elsas A., Peltenburg L.T.C., Schrier P.I.
p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis.
Br. J. Cancer 79:921-926(1999)

PubMed=15048078; DOI=10.1038/sj.onc.1207563
Pavey S., Johansson P., Packer L., Taylor J., Stark M.S., Pollock P.M., Walker G.J., Boyle G.M., Harper U., Cozzi S.-J., Hansen K., Yudt L., Schmidt C., Hersey P., Ellem K.A.O., O'Rourke M.G.E., Parsons P.G., Meltzer P.S., Ringner M., Hayward N.K.
Microarray expression profiling in melanoma reveals a BRAF mutation signature.
Oncogene 23:4060-4067(2004)

PubMed=17363583; DOI=10.1158/0008-5472.CAN-06-4152
Stark M.S., Hayward N.K.
Genome-wide loss of heterozygosity and copy number analysis in melanoma using high-density single-nucleotide polymorphism arrays.
Cancer Res. 67:2632-2642(2007)

PubMed=17516929; DOI=10.1111/j.1600-0749.2007.00375.x
Johansson P., Pavey S., Hayward N.K.
Confirmation of a BRAF mutation-associated gene expression signature in melanoma.
Pigment Cell Res. 20:216-221(2007)

Cross-references
Cell line collections CBA; CBA-1349
ECACC; 10092318
Cell line databases/resources Cell_Model_Passport; SIDM01373
DepMap; ACH-001568
Biological sample resources BioSample; SAMN07624428
Encyclopedic resources Wikidata; Q54906119
Gene expression databases GEO; GSM162932
GEO; GSM226660
Polymorphism and mutation databases Cosmic; 889020
Cosmic; 928736
Cosmic; 1418457
IARC_TP53; 10957
Progenetix; CVCL_2607
Entry history
Entry creation04-Apr-2012
Last entry update16-Dec-2021
Version number20