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Cellosaurus MOG-G-UVW (CVCL_2614)

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Cell line name MOG-G-UVW
Synonyms MOG-GUVW; MOGGUVW; GO-G-UVW; G-UVW; UVW; Medical Oncology Glascow-Glioma-UVW
Accession CVCL_2614
Resource Identification Initiative To cite this cell line use: MOG-G-UVW (RRID:CVCL_2614)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Brain.
Sequence variations Mutation; HGNC; 11998; TP53; Simple; p.Arg110Pro (c.329G>C); ClinVar=VCV000233627; Zygosity=Homozygous (CCLE; Cosmic-CLP).
Genome ancestry Source: PubMed=30894373

Origin% genome
Native American0
East Asian, North2.75
East Asian, South0
South Asian0
European, North58.22
European, South37.14
Disease Anaplastic astrocytoma (NCIt: C9477)
Anaplastic astrocytoma (ORDO: Orphanet_251589)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; PubMed=25877200

Penta D9,13
Penta E5,7

Run an STR similarity search on this cell line

Mackie A.E., Freshney R.I., Akturk F., Hunt G.
Glucocorticoids and the cell surface of human glioma cells: relationship to cytostasis.
Br. J. Cancer 58 Suppl. 9:101-107(1988)

Merzak A., Koochekpour S., Pilkington G.J.
CD44 mediates human glioma cell adhesion and invasion in vitro.
Cancer Res. 54:3988-3992(1994)

PubMed=7591247; DOI=10.1002/ijc.2910630325
Koochekpour S., Pilkington G.J., Merzak A.
Hyaluronic acid/CD44H interaction induces cell detachment and stimulates migration and invasion of human glioma cells in vitro.
Int. J. Cancer 63:450-454(1995)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cell line collections ECACC; 86022703
Cell line databases/resources CLDB; cl3513
Cell_Model_Passport; SIDM00504
Cosmic-CLP; 908145
DepMap; ACH-001126
Ontologies CLO; CLO_0007818
Biological sample resources BioSample; SAMN03470987
BioSample; SAMN10988296
Chemistry resources ChEMBL-Cells; CHEMBL3308137
ChEMBL-Targets; CHEMBL1075508
GDSC; 908145
PharmacoDB; MOGGUVW_949_2019
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM827433
GEO; GSM1374687
GEO; GSM1670123
Other Wikidata; Q54906313
Polymorphism and mutation databases Cosmic; 908145
Cosmic; 2367539
IARC_TP53; 21510
Progenetix; CVCL_2614
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number27