Cellosaurus OE21 (CVCL_2661)

Cell line name OE21
Synonyms OE-21; JROECL 21; JROECL21
Accession CVCL_2661
Resource Identification Initiative To cite this cell line use: OE21 (RRID:CVCL_2661)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: KuDOS 95 cell line panel.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Esophageal squamous cell carcinoma (NCIt: C4024)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; ECACC; PubMed=25877200

Markers:
AmelogeninX (Cosmic-CLP)
X,Y (ECACC; PubMed=25877200)
CSF1PO11,12
D13S31712
D16S53912,13 (Cosmic-CLP; PubMed=25877200)
13 (ECACC)
D18S5119
D19S43315.2
D21S1130,31
D2S133817,19
D3S135817
D5S81813 (Cosmic-CLP)
12,13 (ECACC; PubMed=25877200)
D7S82011,12
D8S117912
FGA20
Penta D11,12
Penta E12
TH017,8 (Cosmic-CLP)
8 (ECACC; PubMed=25877200)
TPOX8,11
vWA15,16 (Cosmic-CLP)
16,17 (ECACC; PubMed=25877200)
Publications

PubMed=9010035; DOI=10.1038/bjc.1997.42
Rockett J.C., Larkin K., Darnton S.J., Morris A.G., Matthews H.R.
Five newly established oesophageal carcinoma cell lines: phenotypic and immunological characterization.
Br. J. Cancer 75:258-263(1997)

PubMed=16364037; DOI=10.1111/j.1442-2050.2006.00530.x
Su M., Chin S.-F., Li X.-Y., Edwards P., Caldas C., Fitzgerald R.C.
Comparative genomic hybridization of esophageal adenocarcinoma and squamous cell carcinoma cell lines.
Dis. Esophagus 19:10-14(2006)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections ECACC; 96062201
Cell line databases/resources CLDB; cl5089
CCLE; OE21_OESOPHAGUS
Cosmic-CLP; 1298359
GDSC; 1298359
IGRhCellID; OE21
LINCS_LDP; LCL-1558
Ontologies BTO; BTO:0004489
CLO; CLO_0008239
EFO; EFO_0002309
Biological sample resources BioSample; SAMN03472891
Gene expression databases GEO; GSM827300
GEO; GSM888556
GEO; GSM1374796
GEO; GSM1374797
GEO; GSM1375727
GEO; GSM1375728
GEO; GSM1375729
GEO; GSM1375730
GEO; GSM1375739
GEO; GSM1375740
GEO; GSM1375741
GEO; GSM1375742
GEO; GSM1375751
GEO; GSM1375752
GEO; GSM1375753
GEO; GSM1375754
GEO; GSM1670303
Polymorphism and mutation databases Cosmic; 1339912
Cosmic; 1995601
Cosmic; 2009522