ID   Ramos-AW
AC   CVCL_2702
SY   RAMOS-AW; AW-Ramos; AW-Ra #1
DR   BTO; BTO:0003077
DR   CLO; CLO_0008741
DR   CLDB; cl4099
DR   ECACC; 85062003
DR   Wikidata; Q54949201
RX   PubMed=62724;
RX   PubMed=181343;
RX   PubMed=2835030;
RX   PubMed=3518877;
CC   Population: Caucasian.
CC   Virology: EBV-negative cell line infected with EBV from P3HR-1 cell line (Cellosaurus=CVCL_2676).
CC   Sequence variation: Gene fusion; HGNC; 5477; IGH + HGNC; 7553; MYC; Name(s)=MYC-IGH (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Ile254Asp (c.760_761AT>GA); Zygosity=Homozygous (from parent cell line).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
ST   Source(s): ECACC
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 13,14
ST   D16S539: 10,13
ST   D5S818: 7,12
ST   D7S820: 11
ST   TH01: 7,9.3
ST   TPOX: 8,9
ST   vWA: 15,16
DI   NCIt; C2912; Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0597 ! Ramos
SX   Male
AG   3Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 22
//
RX   PubMed=62724; DOI=10.1002/ijc.2910180513;
RA   Klein G., Zeuthen J., Terasaki P.I., Billing R.J., Honig R., Jondal M.,
RA   Westman A., Clements G.B.;
RT   "Inducibility of the Epstein-Barr virus (EBV) cycle and surface marker
RT   properties of EBV-negative lymphoma lines and their in vitro
RT   EBV-converted sublines.";
RL   Int. J. Cancer 18:639-652(1976).
//
RX   PubMed=181343; DOI=10.1159/000149930;
RA   Klein G., Giovanella B.C., Westman A., Stehlin J.S. Jr., Mumford D.M.;
RT   "An EBV-genome-negative cell line established from an American Burkitt
RT   lymphoma; receptor characteristics. EBV infectibility and permanent
RT   conversion into EBV-positive sublines by in vitro infection.";
RL   Intervirology 5:319-334(1975).
//
RX   PubMed=2835030; DOI=10.1016/s0385-8146(87)80025-1;
RA   Takimoto T., Sato H., Ogura H., Miyazaki T.;
RT   "Establishment of an Epstein-Barr virus (EBV) genome-positive subline
RT   of Ramos (Ramos/NPC) following infection of Ramos with nasopharyngeal
RT   carcinoma (NPC)-derived EBV.";
RL   Auris Nasus Larynx 14:87-92(1987).
//
RX   PubMed=3518877; DOI=10.3109/07357908609038260;
RA   Fogh J.;
RT   "Human tumor lines for cancer research.";
RL   Cancer Invest. 4:157-184(1986).
//