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Cellosaurus TK6TGR (CVCL_2733)

[Text version]
Cell line name TK6TGR
Synonyms TK6 TGr.p1
Accession CVCL_2733
Resource Identification Initiative To cite this cell line use: TK6TGR (RRID:CVCL_2733)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Transformant: ChEBI; CHEBI:132982; Acridine half-mustard dihydrochloride (6-chloro-9-[3-(2-chloroethylamino)propylamino]-2-methoxyacridine dihydrochloride; Acridine mutagen ICR 191).
Derived from site: In situ; Spleen; UBERON=UBERON_0002106.
Sequence variations
  • Mutation; HGNC; 11272; SPTA1; Simple; p.Ser1163Ala (c.3487T>G); ClinVar=VCV000258929; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11830; TK1; Simple; p.Ala78Argfs*27 (c.231insC); Zygosity=Heterozygous (from parent cell line).
Disease Hereditary spherocytosis (NCIt: C97074)
Hereditary spherocytosis (ORDO: Orphanet_822)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0561 (TK6)
Sex of cell Male
Age at sampling 5Y
Category Transformed cell line
STR profile Source(s): ECACC

Markers:
AmelogeninX,Y
CSF1PO11,12
D5S81812,13
D7S8209,11
D13S31711
D16S53911,12
TH018,9.3
TPOX8,11
vWA17,20

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Publications

PubMed=22359172; DOI=10.1007/BF00365082
Clark S.A., James S.E., Fitchett M.
A new parental cell line for human x human hybridoma production.
Cytotechnology 1:359-363(1988)

Cross-references
Cell line collections (Providers) ECACC; 87020507
Cell line databases/resources CLO; CLO_0009358
CLDB; cl4520
Encyclopedic resources Wikidata; Q54972537
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number17