ID   TR146
AC   CVCL_2736
SY   Tr146; TR-146; TR 146
DR   BTO; BTO:0002718
DR   Cosmic; 948039
DR   Cosmic; 2131857
DR   ECACC; 10032305
DR   Wikidata; Q54972930
DR   Ximbio; 151425
RX   DOI=10.1016/B978-0-12-333530-2.50007-1;
RX   PubMed=2413234;
RX   PubMed=21868764;
RX   PubMed=26754630;
RX   PubMed=28196595;
RX   PubMed=29156801;
WW   http://tcpaportal.org/mclp/
CC   Part of: MD Anderson Cell Lines Project.
CC   Doubling time: 22 hours (PubMed=2413234).
CC   Omics: Deep exome analysis.
CC   Omics: Deep RNAseq analysis.
CC   Omics: Protein expression by reverse-phase protein arrays.
CC   Derived from metastatic site: Cervical lymph node.
ST   Source(s): ECACC; PubMed=21868764
ST   Amelogenin: X
ST   CSF1PO: 11,13
ST   D13S317: 11,14
ST   D16S539: 13
ST   D5S818: 10,11
ST   D7S820: 10,12
ST   TH01: 9
ST   TPOX: 8,9
ST   vWA: 15,18
DI   NCIt; C4040; Buccal mucosa squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Female
AG   67Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 13-11-18; Version: 17
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RX   DOI=10.1016/B978-0-12-333530-2.50007-1;
RA   Carey T.E.;
RT   "Head and neck tumor cell lines.";
RL   (In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.79-120; Academic Press; New York (1994).
//
RX   PubMed=2413234; DOI=10.1093/jnci/75.4.621;
RA   Rupniak H.T., Rowlatt C., Lane E.B., Steele J.G., Trejdosiewicz L.K.,
RA   Laskiewicz B., Povey S., Hill B.T.;
RT   "Characteristics of four new human cell lines derived from squamous
RT   cell carcinomas of the head and neck.";
RL   J. Natl. Cancer Inst. 75:621-635(1985).
//
RX   PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690;
RA   Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C.,
RA   Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G.,
RA   Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.;
RT   "Assembly and initial characterization of a panel of 85 genomically
RT   validated cell lines from diverse head and neck tumor sites.";
RL   Clin. Cancer Res. 17:7248-7264(2011).
//
RX   PubMed=26754630; DOI=10.1186/s13046-016-0284-4;
RA   Hyakusoku H., Sano D., Takahashi H., Hatano T., Isono Y., Shimada S.,
RA   Ito Y., Myers J.N., Oridate N.;
RT   "JunB promotes cell invasion, migration and distant metastasis of head
RT   and neck squamous cell carcinoma.";
RL   J. Exp. Clin. Cancer Res. 35:6-6(2016).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005;
RA   Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P.,
RA   Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W.,
RA   Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D.,
RA   Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B.,
RA   Liang H.;
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//
RX   PubMed=29156801; DOI=10.18632/oncotarget.21174;
RA   Kalu N.N., Mazumdar T., Peng S., Shen L., Sambandam V., Rao X., Xi Y.,
RA   Li L., Qi Y., Gleber-Netto F.O., Patel A., Wang J., Frederick M.J.,
RA   Myers J.N., Pickering C.R., Johnson F.M.;
RT   "Genomic characterization of human papillomavirus-positive and
RT   -negative human squamous cell cancer cell lines.";
RL   Oncotarget 8:86369-86383(2017).
//