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Cellosaurus U-BLC1 (CVCL_2738)

[Text version]

Cell line name U-BLC1
Synonyms UBLC1
Accession CVCL_2738
Resource Identification Initiative To cite this cell line use: U-BLC1 (RRID:CVCL_2738)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Omics: Deep exome analysis.
Omics: Deep quantitative proteome analysis.
Omics: Deep RNAseq analysis.
Sequence variations Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=24035680).
Mutation; HGNC; 11998; TP53; Simple; p.His296Tyr (c.886C>T); ClinVar=VCV000132973; Zygosity=Homozygous (CCLE).
Mutation; HGNC; 11998; TP53; Simple; p.Gln331Ter (c.991C>T); ClinVar=VCV000922893; Zygosity=Homozygous (CCLE).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 84Y
Category Cancer cell line
Publications

PubMed=10074925; DOI=10.1002/(SICI)1097-0215(19990315)80:6<903::AID-IJC17>3.0.CO;2-8
Bruch J., Wohr G., Bruderlein S., Barbi G., Wolter H., Dixkens C., Mattfeldt T., Moller P., Paiss T., Hautmann R., Vogel W., Hameister H.
Detailed marker chromosome analysis in cell line U-BLC1, established from transitional-cell carcinoma of the bladder.
Int. J. Cancer 80:903-910(1999)

PubMed=24367658; DOI=10.1371/journal.pone.0084411
Ross R.L., Burns J.E., Taylor C.F., Mellor P., Anderson D.H., Knowles M.A.
Identification of mutations in distinct regions of p85 alpha in urothelial cancer.
PLoS ONE 8:E84411-E84411(2013)

PubMed=24035680; DOI=10.1016/j.eururo.2013.08.057
Hurst C.D., Platt F.M., Knowles M.A.
Comprehensive mutation analysis of the TERT promoter in bladder cancer and detection of mutations in voided urine.
Eur. Urol. 65:367-369(2014)

PubMed=29732388; DOI=10.3233/BLC-180167
Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

PubMed=31978347; DOI=10.1016/j.cell.2019.12.023
Nusinow D.P., Szpyt J., Ghandi M., Rose C.M., McDonald E.R. III, Kalocsay M., Jane-Valbuena J., Gelfand E., Schweppe D.K., Jedrychowski M., Golji J., Porter D.A., Rejtar T., Wang Y.K., Kryukov G.V., Stegmeier F., Erickson B.K., Garraway L.A., Sellers W.R., Gygi S.P.
Quantitative proteomics of the Cancer Cell Line Encyclopedia.
Cell 180:387-402.e16(2020)

Cross-references
Cell line collections ECACC; 06013102
Cell line databases/resources CCLE; UBLC1_URINARY_TRACT
DepMap; ACH-000741
Biological sample resources BioSample; SAMN10987727
Chemistry resources PharmacoDB; UBLC1_1625_2019
Gene expression databases ArrayExpress; E-MTAB-2770
Other Wikidata; Q54973609
Polymorphism and mutation databases Cosmic; 2050467
Cosmic; 2212693
IARC_TP53; 28257
IARC_TP53; 28265
LiGeA; CCLE_374
Entry history
Entry creation04-Apr-2012
Last entry update23-Sep-2021
Version number18