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Cellosaurus UM-RC-6 (CVCL_2741)

[Text version]

Cell line name UM-RC-6
Synonyms UMRC-6; UMRC6; University of Michigan-Renal Carcinoma-6
Accession CVCL_2741
Resource Identification Initiative To cite this cell line use: UM-RC-6 (RRID:CVCL_2741)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~43 hours (PubMed=4038766).
Sequence variations VHL p.Val170fs*31 (c.502_511del10) (PubMed=8493574).
Disease Renal cell carcinoma (NCIt: C9385)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ECACC; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO8,12
D2S133819,22
D3S135816
D5S81812
D7S82010,12
D8S117912,13
D13S31712
D16S5399,10
D18S5118
D19S43314,18.2
D21S1128
FGA22
Penta D7
Penta E8
TH016
TPOX10
vWA18

Run an STR similarity search on this cell line
Web pages http://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/u/cell-lines-detail-317.html
Publications

PubMed=4038766; DOI=10.1002/jso.2930280320
Grossman H.B., Wedemeyer G., Ren L.Q.
Human renal carcinoma: characterization of five new cell lines.
J. Surg. Oncol. 28:237-244(1985)

PubMed=8493574; DOI=10.1126/science.8493574
Latif F., Tory K., Gnarra J., Yao M., Duh F.-M., Orcutt M.L., Stackhouse T., Kuzmin I., Modi W., Geil L., Schmidt L., Zhou F., Li H., Wei M.H., Chen F., Glenn G., Choyke P., Walther M.M., Weng Y., Duan D.-S.R., Dean M., Glavac D., Richards F.M., Crossey P.A., Ferguson-Smith M.A., le Paslier D., Chumakov I., Cohen D., Chinault A.C., Maher E.R., Linehan W.M., Zbar B., Lerman M.I.
Identification of the von Hippel-Lindau disease tumor suppressor gene.
Science 260:1317-1320(1993)

PubMed=7915601; DOI=10.1038/ng0594-85
Gnarra J.R., Tory K., Weng Y., Schmidt L., Wei M.H., Li H., Latif F., Liu S., Chen F., Duh F.-M., Lubensky I.A., Duan D.R., Florence C., Pozzatti R., Walther M.M., Bander N.H., Grossman H.B., Brauch H., Pomer S., Brooks J.D., Isaacs W.B., Lerman M.I., Zbar B., Linehan W.M.
Mutations of the VHL tumour suppressor gene in renal carcinoma.
Nat. Genet. 7:85-90(1994)

PubMed=28489074; DOI=10.1038/ncomms15165
Sinha R., Winer A.G., Chevinsky M., Jakubowski C., Chen Y.-B., Dong Y., Tickoo S.K., Reuter V.E., Russo P., Coleman J.A., Sander C., Hsieh J.J., Hakimi A.A.
Analysis of renal cancer cell lines from two major resources enables genomics-guided cell line selection.
Nat. Commun. 8:15165-15165(2017)

Cross-references
Cell line collections ECACC; 08090513
Cell line databases/resources CCLE; UMRC6_KIDNEY
Biological sample resources BioSample; SAMN03470958
Gene expression databases GEO; GSM374477
Other Wikidata; Q54990787
Polymorphism and mutation databases Cosmic; 972873
Cosmic; 972913
Cosmic; 1779196