ID   WI-38 VA13 subline 2RA
AC   CVCL_2759
SY   WI 38 VA13 subline 2RA; WI 38 VA-13 subline 2RA; WI 38VA13 subline 2RA; WI-38 VA13 sub 2 RA; WI38-VA13 subline 2RA; WI38 VA13/2RA; WI38VA13/2RA; VA13 2RA; WI-38 VA13; WI 38 VA 13; WI38-VA13; WI38/VA13; WI38VA13; VA-13; VA13; AG07217; AG7217
DR   BTO; BTO:0003066
DR   CLO; CLO_0009597
DR   CLO; CLO_0009598
DR   CLO; CLO_0009599
DR   CLO; CLO_0035575
DR   CLO; CLO_0050044
DR   CLDB; cl4711
DR   CLDB; cl4712
DR   CLDB; cl4713
DR   CLDB; cl4714
DR   ATCC; CCL-75.1
DR   BCRC; 60504
DR   BioSample; SAMN03471286
DR   cancercelllines; CVCL_2759
DR   CCRID; 1101HUM-PUMC000390
DR   CCRID; 4201HUM-CCTCC00122
DR   CCTCC; GDC0122
DR   ChEMBL-Cells; CHEMBL3308010
DR   ChEMBL-Targets; CHEMBL612807
DR   CLS; 300421
DR   Coriell; AG07217
DR   ECACC; 85062512
DR   GEO; GSM784286
DR   GEO; GSM3048734
DR   GEO; GSM3048735
DR   GEO; GSM3048736
DR   GEO; GSM3048737
DR   IZSLER; BS CL 91
DR   JCRB; JCRB9057
DR   KCLB; 10075.1
DR   Progenetix; CVCL_2759
DR   PubChem_Cell_line; CVCL_2759
DR   RCB; RCB0251
DR   TOKU-E; 3451
DR   Wikidata; Q54994032
RX   CelloPub=CLPUB00597;
RX   DOI=10.2307/1308677;
RX   PubMed=656543;
RX   PubMed=699332;
RX   PubMed=1372102;
RX   PubMed=1702221;
RX   PubMed=3002148;
RX   PubMed=3413074;
RX   PubMed=4290661;
RX   PubMed=6256643;
RX   PubMed=6538202;
RX   PubMed=7065527;
RX   PubMed=9175740;
RX   PubMed=24116068;
CC   Population: Caucasian; Swedish.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Fetal lung; UBERON=UBERON_0005597.
CC   Cell type: Fibroblast of lung; CL=CL_0002553.
ST   Source(s): ATCC; CCRID; CLS; JCRB; KCLB; PubMed=24116068; RCB
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 11
ST   D16S539: 11,12
ST   D18S51: 16,18
ST   D19S433: 13,16.2
ST   D21S11: 30,30.2
ST   D2S1338: 19,25
ST   D3S1358: 16,17
ST   D5S818: 10
ST   D7S820: 9,11
ST   D8S1179: 14
ST   FGA: 22,24
ST   Penta D: 13
ST   Penta E: 13,14
ST   TH01: 9.3
ST   TPOX: 8
ST   vWA: 19,20
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0579 ! WI-38
SX   Female
AG   16FW
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 35
//
RX   CelloPub=CLPUB00597;
RG   National Institute on Aging;
RT   "1994 catalog of cell lines. NIA Aging Cell Repository.";
RL   (In) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda (1994).
//
RX   DOI=10.2307/1308677;
RA   Day R.S. III;
RT   "Adenovirus: a probe for human cells deficient in DNA repair.";
RL   BioScience 31:807-813(1981).
//
RX   PubMed=656543; DOI=10.1016/S0006-3495(78)85487-3;
RA   Ehmann U.K., Cook K.H., Friedberg E.C.;
RT   "The kinetics of thymine dimer excision in ultraviolet-irradiated
RT   human cells.";
RL   Biophys. J. 22:249-264(1978).
//
RX   PubMed=699332; DOI=10.1016/0009-8981(78)90444-8;
RA   Knaup G., Pfleiderer G., Bayreuther K.;
RT   "Human diploid lung fibroblast cell lines WI 26 and WI 38 exhibit
RT   isozyme shift of alkaline phosphatase after viral transformation.";
RL   Clin. Chim. Acta 88:375-383(1978).
//
RX   PubMed=1372102; DOI=10.1016/0921-8777(92)90080-M;
RA   Satokata I., Tanaka K., Miura N., Narita M., Mimaki T., Satoh Y.,
RA   Kondo S., Okada Y.;
RT   "Three nonsense mutations responsible for group A xeroderma
RT   pigmentosum.";
RL   Mutat. Res. 273:193-202(1992).
//
RX   PubMed=1702221; DOI=10.1073/pnas.87.24.9908;
RA   Satokata I., Tanaka K., Miura N., Miyamoto I., Satoh Y., Kondo S.,
RA   Okada Y.;
RT   "Characterization of a splicing mutation in group A xeroderma
RT   pigmentosum.";
RL   Proc. Natl. Acad. Sci. U.S.A. 87:9908-9912(1990).
//
RX   PubMed=3002148; DOI=10.1007/978-1-4684-7853-2_15;
RA   Matsumura T., Nagata M., Konishi R., Goto M.;
RT   "Studies of SV40-infected Werner syndrome fibroblasts.";
RL   Adv. Exp. Med. Biol. 190:313-330(1985).
//
RX   PubMed=3413074; DOI=10.1073/pnas.85.16.6042;
RA   Pereira-Smith O.M., Smith J.R.;
RT   "Genetic analysis of indefinite division in human cells:
RT   identification of four complementation groups.";
RL   Proc. Natl. Acad. Sci. U.S.A. 85:6042-6046(1988).
//
RX   PubMed=4290661;
RA   Girardi A.J., Weinstein D., Moorhead P.S.;
RT   "SV40 transformation of human diploid cells. A parallel study of viral
RT   and karyologic parameters.";
RL   Ann. Med. Exp. Biol. Fenn. 44:242-254(1966).
//
RX   PubMed=6256643; DOI=10.1038/288724a0;
RA   Day R.S. III, Ziolkowski C.H.J., Scudiero D.A., Meyer S.A.,
RA   Lubiniecki A.S., Girardi A.J., Galloway S.M., Bynum G.D.;
RT   "Defective repair of alkylated DNA by human tumour and
RT   SV40-transformed human cell strains.";
RL   Nature 288:724-727(1980).
//
RX   PubMed=6538202; DOI=10.1083/jcb.98.3.1133;
RA   Azzarone B., Suarez H., Mingari M.C., Moretta L., Fauci A.S.;
RT   "4F2 monoclonal antibody recognizes a surface antigen on spread human
RT   fibroblasts of embryonic but not of adult origin.";
RL   J. Cell Biol. 98:1133-1137(1984).
//
RX   PubMed=7065527; DOI=10.1164/arrd.1982.125.2.222;
RA   Hay R.J., Williams C.D., Macy M.L., Lavappa K.S.;
RT   "Cultured cell lines for research on pulmonary physiology available
RT   through the American Type Culture Collection.";
RL   Am. Rev. Respir. Dis. 125:222-232(1982).
//
RX   PubMed=9175740; DOI=10.1093/hmg/6.6.921;
RA   Bryan T.M., Marusic L., Bacchetti S., Namba M., Reddel R.R.;
RT   "The telomere lengthening mechanism in telomerase-negative immortal
RT   human cells does not involve the telomerase RNA subunit.";
RL   Hum. Mol. Genet. 6:921-926(1997).
//
RX   PubMed=24116068; DOI=10.1371/journal.pone.0075692;
RA   Weiskirchen R., Weimer J., Meurer S.K., Kron A., Seipel B., Vater I.,
RA   Arnold N., Siebert R., Xu L.-M., Friedman S.L., Bergmann C.;
RT   "Genetic characteristics of the human hepatic stellate cell line LX-2.";
RL   PLoS ONE 8:E75692-E75692(2013).
//