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Cellosaurus HO-1-u-1 (CVCL_2784)

[Text version]

Cell line name HO-1-u-1
Synonyms HO-1-U-1; Ho-1-u-1; HO1-U-1; HO1-U1; HO1U1; HO1u1; Ho1u1; Ueda-1
Accession CVCL_2784
Resource Identification Initiative To cite this cell line use: HO-1-u-1 (RRID:CVCL_2784)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Misspelling: HO1-UI; In Cosmic 2546834.
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.54
Native American0
East Asian, North76.45
East Asian, South19.98
South Asian0.41
European, North1.61
European, South0
Disease Floor of mouth squamous cell carcinoma (NCIt: C4041)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; JCRB; RCB; TKG

Markers:
AmelogeninX,Y
CSF1PO10
D5S81810
D7S8209,10
D13S3179
D16S53912
TH019
TPOX10
vWA17,19

Run an STR similarity search on this cell line
Publications

DOI=10.5794/jjoms.31.1347
Miyauchi S., Moroyama T., Sakamoto T., Okamoto T., Takada K.
Establishment of human tumor cell line (Ueda-1) derived from squamous cell carcinoma of the floor of the mouth.
Nihon Koku Geka Gakkai Zasshi 31:1347-1351(1985)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=12738951; DOI=10.1067/moe.2003.36
Sugiyama M., Bhawal U.K., Dohmen T., Ono S., Miyauchi M., Ishikawa T.
Detection of human papillomavirus-16 and HPV-18 DNA in normal, dysplastic, and malignant oral epithelium.
Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 95:594-600(2003)

PubMed=17325662; DOI=10.1038/sj.onc.1210330
Nakaya K., Yamagata H.D., Arita N., Nakashiro K.-I., Nose M., Miki T., Hamakawa H.
Identification of homozygous deletions of tumor suppressor gene FAT in oral cancer using CGH-array.
Oncogene 26:5300-5308(2007)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections JCRB; JCRB0828
RCB; RCB2102
TKG; TKG 0455
Cell line databases/resources CCLE; HO1U1_UPPER_AERODIGESTIVE_TRACT
Cell_Model_Passport; SIDM00591
Cosmic-CLP; 753561
DepMap; ACH-002045
GDSC; 753561
LINCS_LDP; LCL-1202
Ontologies BTO; BTO:0005948
CLO; CLO_0051384
Biological sample resources BioSample; SAMN01821683
BioSample; SAMN03472521
Chemistry resources PharmacoDB; HO1u1_560_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM827216
GEO; GSM850381
GEO; GSM1669889
Other Wikidata; Q54890083
Polymorphism and mutation databases Cosmic; 753561
Cosmic; 1118792
Cosmic; 1120707
Cosmic; 1530742
Cosmic; 1571800
Cosmic; 1995441
Cosmic; 2266788
Cosmic; 2546834
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number27