Cellosaurus JHH-6 (CVCL_2788)

Cell line name JHH-6
Synonyms Jhh-6; JHH6
Accession CVCL_2788
Resource Identification Initiative To cite this cell line use: JHH-6 (RRID:CVCL_2788)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: MD Anderson Cell Lines Project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Hepatocellular carcinoma (NCIt: C3099)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; JCRB; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10,12
D13S31711,12,13
D16S53910
D18S5120
D19S43313
D21S1131,32.2
D2S133819,24
D3S135817
D5S81810,11
D7S82011
D8S117912,13
FGA22
Penta D10,13
Penta E15
TH017,9
TPOX8,9
vWA14,18
Web pages http://tcpaportal.org/mclp/
Publications

PubMed=1701409
Fujise K., Nagamori S., Hasumura S., Homma S., Sujino H., Matsuura T., Shimizu K., Niiya M., Kameda H., Fujita K., Ohno T.
Integration of hepatitis B virus DNA into cells of six established human hepatocellular carcinoma cell lines.
Hepato-Gastroenterol. 37:457-460(1990)

PubMed=10933057; DOI=10.1038/sj.neo.7900046
Murakami K., Sakukawa R., Ikeda T., Matsuura T., Hasumura S., Nagamori S., Yamada Y., Saiki I.
Invasiveness of hepatocellular carcinoma cell lines: contribution of membrane-type 1 matrix metalloproteinase.
Neoplasia 1:424-430(1999)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=23505090; DOI=10.1002/hep.26402
Wang K., Lim H.Y., Shi S., Lee J., Deng S., Xie T., Zhu Z., Wang Y., Pocalyko D., Yang W.J., Rejto P.A., Mao M., Park C.-K., Xu J.
Genomic landscape of copy number aberrations enables the identification of oncogenic drivers in hepatocellular carcinoma.
Hepatology 58:706-717(2013)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P., Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections JCRB; JCRB1030
JCRB; NIHS0280 - Discontinued
Cell line databases/resources CCLE; JHH6_LIVER
Cosmic-CLP; 1240159
GDSC; 1240159
LINCS_HMS; 50021
LINCS_LDP; LCL-1923
Biological sample resources BioSample; SAMN03472917
Gene expression databases GEO; GSM827199
GEO; GSM887173
GEO; GSM888245
GEO; GSM936768
GEO; GSM1669953
Polymorphism and mutation databases Cosmic; 1995463
Cosmic; 2023876