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Cellosaurus V79-4 (CVCL_2796)

[Text version]
Cell line name V79-4
Synonyms V-79-4; V 79-4
Accession CVCL_2796
Resource Identification Initiative To cite this cell line use: V79-4 (RRID:CVCL_2796)
Comments Group: Space-flown cell line (cellonaut).
Characteristics: Widely used to study DNA damage induced by X-ray, UV radiation and oxidizing agents.
Doubling time: 12-14 hours (ECACC=93010723).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (PubMed=9023109).
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (PubMed=9023109).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_UK06 (V79-122D1)
Children:
CVCL_1N51 (irs1)CVCL_1N52 (irs2)CVCL_1N53 (irs3)
CVCL_5A65 (V79-ETO1)CVCL_5A66 (V79-ETO2)CVCL_5A67 (V79-ETO3)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=5392645; DOI=10.1093/genetics/62.2.359
Chu E.H.-Y., Brimer P.A., Jacobson K.B., Merriam E.V.
Mammalian cell genetics. I. Selection and characterization of mutations auxotrophic for L-glutamine or resistant to 8-azaguanine in Chinese hamster cells in vitro.
Genetics 62:359-377(1969)

PubMed=301865; DOI=10.1080/09553007714550661
Cox R., Thacker J., Goodhead D.T.
Inactivation and mutation of cultured mammalian cells by aluminium characteristic ultrasoft X-rays. II. Dose-responses of Chinese hamster and human diploid cells to aluminium X-rays and radiations of different LET.
Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 31:561-576(1977)

PubMed=9023109; DOI=10.1093/nar/25.5.992
Chaung W., Mi L.-J., Boorstein R.J.
The p53 status of Chinese hamster V79 cells frequently used for studies on DNA damage and DNA repair.
Nucleic Acids Res. 25:992-994(1997)

Cross-references
Cell line collections (Providers) ATCC; CCL-93
BCRC; 60183
BCRJ; 0244
CLS; 603371
ECACC; 93010723
JCRB; JCRB0603
RCB; RCB2332
Cell line databases/resources CLO; CLO_0009504
CLO; CLO_0051576
CLDB; cl4632
Anatomy/cell type resources BTO; BTO:0003719
Chemistry resources ChEMBL-Cells; CHEMBL3307246
ChEMBL-Targets; CHEMBL612801
PubChem_Cell_line; CVCL_2796
Encyclopedic resources Wikidata; Q54992586
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number26