Home  |  Contact

Cellosaurus KNS-60 (CVCL_2798)

[Text version]

Cell line name KNS-60
Synonyms KNS 60; KNS60
Accession CVCL_2798
Resource Identification Initiative To cite this cell line use: KNS-60 (RRID:CVCL_2798)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: 42 hours (CelloPub=CLPUB00152); 38 hours (PubMed=25984343).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: shRNA library screening.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0
East Asian, North80.41
East Asian, South18.86
South Asian0
European, North0
European, South0.73
Disease Glioblastoma (NCIt: C3058)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 55Y
Category Cancer cell line
STR profile Source(s): JCRB; PubMed=25877200

Markers:
AmelogeninX
CSF1PO12
D2S133825
D3S135816,18
D5S81811
D7S8209,12 (JCRB)
9 (PubMed=25877200)
D8S117914
D13S3178
D16S53910,11
D18S5115
D19S43313
D21S1129
FGA18
Penta D9,10
Penta E8
TH017,8 (JCRB)
7 (PubMed=25877200)
TPOX9
vWA15,19

Run an STR similarity search on this cell line
Publications

CLPUB00152
Takeshita I., Takaki T., Nakamura T., Maeyama R., Fukui M., Kitamura K.
Established cell lines derived from human gliomas.
Hum. Cell 3:255-256(1990)

PubMed=16232199; DOI=10.1111/j.1349-7006.2005.00099.x
Saigusa K., Hashimoto N., Tsuda H., Yokoi S., Maruno M., Yoshimine T., Aoyagi M., Ohno K., Imoto I., Inazawa J.
Overexpressed Skp2 within 5p amplification detected by array-based comparative genomic hybridization is associated with poor prognosis of glioblastomas.
Cancer Sci. 96:676-683(2005)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=25984343; DOI=10.1038/sdata.2014.35
Cowley G.S., Weir B.A., Vazquez F., Tamayo P., Scott J.A., Rusin S., East-Seletsky A., Ali L.D., Gerath W.F.J., Pantel S.E., Lizotte P.H., Jiang G., Hsiao J., Tsherniak A., Dwinell E., Aoyama S., Okamoto M., Harrington W., Gelfand E., Green T.M., Tomko M.J., Gopal S., Wong T.C., Li H., Howell S., Stransky N., Liefeld T., Jang D., Bistline J., Hill Meyers B., Armstrong S.A., Anderson K.C., Stegmaier K., Reich M., Pellman D., Boehm J.S., Mesirov J.P., Golub T.R., Root D.E., Hahn W.C.
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Sci. Data 1:140035-140035(2014)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections JCRB; IFO50357
Cell line databases/resources CCLE; KNS60_CENTRAL_NERVOUS_SYSTEM
Cell_Model_Passport; SIDM01494
CGH-DB; 145-1
DepMap; ACH-000445
Biological sample resources BioSample; SAMN03470967
BioSample; SAMN03472788
BioSample; SAMN10987822
Chemistry resources PharmacoDB; KNS60_774_2019
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887230
GEO; GSM888304
Other Wikidata; Q54900251
Polymorphism and mutation databases Cosmic; 687574
Cosmic; 2367533
Cosmic; 2516021
LiGeA; CCLE_924
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number16