Cellosaurus KNS-81 (CVCL_2799)

Cell line name KNS-81
Synonyms KNS81
Accession CVCL_2799
Resource Identification Initiative To cite this cell line use: KNS-81 (RRID:CVCL_2799)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: 110 hours (PubMed=25984343).
Omics: shRNA library screening.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Glioblastoma (NCIt: C3058)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children: CVCL_1336 (KNS-81-FD)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): JCRB; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO9,12
D13S3179
D16S53910,12
D18S5113,19
D19S43313.2,14
D21S1129,30
D2S133822,23
D3S135814,16
D5S8189,12
D7S82011
D8S117911,17
FGA20,22
Penta D9
Penta E11,15
TH017,9
TPOX8,11
vWA17,18
Publications

CLPUB00152
Takeshita I., Takaki T., Nakamura T., Maeyama R., Fukui M., Kitamura K.
Established cell lines derived from human gliomas.
Hum. Cell 3:255-256(1990)

PubMed=16232199; DOI=10.1111/j.1349-7006.2005.00099.x
Saigusa K., Hashimoto N., Tsuda H., Yokoi S., Maruno M., Yoshimine T., Aoyagi M., Ohno K., Imoto I., Inazawa J.
Overexpressed Skp2 within 5p amplification detected by array-based comparative genomic hybridization is associated with poor prognosis of glioblastomas.
Cancer Sci. 96:676-683(2005)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=25984343; DOI=10.1038/sdata.2014.35
Cowley G.S., Weir B.A., Vazquez F., Tamayo P., Scott J.A., Rusin S., East-Seletsky A., Ali L.D., Gerath W.F.J., Pantel S.E., Lizotte P.H., Jiang G., Hsiao J., Tsherniak A., Dwinell E., Aoyama S., Okamoto M., Harrington W., Gelfand E., Green T.M., Tomko M.J., Gopal S., Wong T.C., Li H., Howell S., Stransky N., Liefeld T., Jang D., Bistline J., Hill Meyers B., Armstrong S.A., Anderson K.C., Stegmaier K., Reich M., Pellman D., Boehm J.S., Mesirov J.P., Golub T.R., Root D.E., Hahn W.C.
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Sci. Data 1:140035-140035(2014)

Cross-references
Cell line collections IFO; IFO50359
Cell line databases/resources CCLE; KNS81_CENTRAL_NERVOUS_SYSTEM
CGH-DB; 146-1
TOKU-E; 4091
Biological sample resources BioSample; SAMN03470965
Gene expression databases GEO; GSM887232
GEO; GSM888306
Polymorphism and mutation databases Cosmic; 687575
Cosmic; 2516022