Cellosaurus ASH-3 (CVCL_2856)

Cell line name ASH-3
Accession CVCL_2856
Resource Identification Initiative To cite this cell line use: ASH-3 (RRID:CVCL_2856)
Comments Doubling time: 84 hours (PubMed=11686581).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Disease Thyroid gland undifferentiated (anaplastic) carcinoma (NCIt: C3878)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; JCRB; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10,14
D13S31712
D16S5399
D18S5113,17
D19S43313,15.2
D21S1128
D2S133819,23
D3S135815
D5S81811,13
D7S82011
D8S117916
FGA20,22
Penta D10,11
Penta E5
TH019
TPOX8,11
vWA16,17
Publications

PubMed=11686581; DOI=10.1016/S0753-3322(01)00087-7
Sekiguchi M., Shiroko Y., Arai T., Kishino T., Sugawara I., Kusakabe T., Suzuki T., Yamashita T., Obara T., Ito K., Hasumi K.
Biological characteristics and chemosensitivity profile of four human anaplastic thyroid carcinoma cell lines.
Biomed. Pharmacother. 55:466-474(2001)

PubMed=23833040; DOI=10.1210/jc.2013-2383
Landa I., Ganly I., Chan T.A., Mitsutake N., Matsuse M., Ibrahimpasic T., Ghossein R.A., Fagin J.A.
Frequent somatic TERT promoter mutations in thyroid cancer: higher prevalence in advanced forms of the disease.
J. Clin. Endocrinol. Metab. 98:E1562-E1566(2013)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections JCRB; JCRB1073
JCRB; NIHS0269 - Discontinued
Cell line databases/resources Cosmic-CLP; 1290722
GDSC; 1290722
LINCS_LDP; LCL-1682
Biological sample resources BioSample; SAMN03470933
Gene expression databases GEO; GSM827189
GEO; GSM1669602
Polymorphism and mutation databases Cosmic; 2054110