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Cellosaurus B2-17 (CVCL_2864)

[Text version]

Cell line name B2-17
Accession CVCL_2864
Resource Identification Initiative To cite this cell line use: B2-17 (RRID:CVCL_2864)
Comments Doubling time: 48 hours (CelloPub=CLPUB00152).
Selected for resistance to: ChEBI; CHEBI:472552; 5-bromo-2'-deoxyuridine (Bromodeoxyuridine; BrdU; BUdR).
Omics: SNP array analysis.
Caution: Was incorrectly reported to be a U-251MG contaminated cell line by ICLAC while it was specifically derived from U-251MG as described in the original publication (CelloPub=CLPUB00152).
Sequence variations PTEN p.Glu242fs*15 (c.723_724insTT) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
TP53 p.Arg273His (c.818G>A) (from parent cell line).
Disease Astrocytoma (NCIt: C60781)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0021 (U-251MG)
Sex of cell Male
Age at sampling 75Y
Category Cancer cell line
STR profile Source(s): JCRB

Markers:
AmelogeninX
CSF1PO11,12
D5S81811,12
D7S82010,12
D13S31710,11
D16S53912
TH019.3
TPOX8
vWA16,18

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Publications

CLPUB00152
Takeshita I., Takaki T., Nakamura T., Maeyama R., Fukui M., Kitamura K.
Established cell lines derived from human gliomas.
Hum. Cell 3:255-256(1990)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

Cross-references
Cell line collections JCRB; IFO50361
Cell line databases/resources Cell_Model_Passport; SIDM00110
LINCS_LDP; LCL-1367
Biological sample resources BioSample; SAMN03151975
Other Wikidata; Q54752556
Polymorphism and mutation databases Cosmic; 911904
Cosmic; 2367508
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number17