Cellosaurus CPT-K5 (CVCL_2878)

Cell line name CPT-K5
Accession CVCL_2878
Resource Identification Initiative To cite this cell line use: CPT-K5 (RRID:CVCL_2878)
Comments Selected for resistance to: ChEBI; CHEBI:27656; Camptothecin (CPT).
Derived from sampling site: Peripheral blood.
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1667 (RPMI-8402)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): JCRB

Markers:
AmelogeninX
CSF1PO9,11,12
D13S31710,12
D16S53910,14
D5S81811,12,13
D7S8209,12,14
TH016,7
TPOX8
vWA17,18,20
Publications

PubMed=3039492; DOI=10.1073/pnas.84.16.5565
Andoh T., Ishii K., Suzuki Y., Ikegami Y., Kusunoki Y., Takemoto Y., Okada K.
Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I.
Proc. Natl. Acad. Sci. U.S.A. 84:5565-5569(1987)

PubMed=14679002
Li T.-K., Houghton P.J., Desai S.D., Daroui P., Liu A.A., Hars E.S., Ruchelman A.L., LaVoie E.J., Liu L.F.
Characterization of ARC-111 as a novel topoisomerase I-targeting anticancer drug.
Cancer Res. 63:8400-8407(2003)

Cross-references
Cell line collections JCRB; JCRB1067
Biological sample resources BioSample; SAMN03472497