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Cellosaurus EJ-1 (CVCL_2893)

[Text version]

Cell line name EJ-1
Synonyms EJ1
Accession CVCL_2893
Resource Identification Initiative To cite this cell line use: EJ-1 (RRID:CVCL_2893)
Comments Problematic cell line: Contaminated. Shown to be a T24 derivative (DOI=10.11418/jtca1981.18.4_329; PubMed=20143388).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00194.
Population: Caucasian; Swedish.
Derived from sampling site: Urinary bladder.
Sequence variations Mutation; HGNC; 5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0554 (T24)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
STR profile Source(s): JCRB; PubMed=11416159; TKG

Markers:
AmelogeninX
CSF1PO10,12
D5S81810,12
D7S82010,11
D8S117914
D13S31712
D16S5399
D18S5116,18
D21S1129
FGA17,22
TH016
TPOX8,11
vWA17

Run an STR similarity search on this cell line
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations_v11_distribution.xlsx
Publications

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

DOI=10.11418/jtca1981.18.4_329
Tanabe H., Takada Y., Minegishi D., Kurematsu M., Masui T., Mizusawa H.
Cell line individualization by STR multiplex system in the cell bank found cross-contamination between ECV304 and EJ-1/T24.
Tissue Cult. Res. Commun. 18:329-338(1999)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line collections JCRB; JCRB0710
RCB; RCB2137 - Discontinued
TKG; TKG 0441
Ontologies BTO; BTO:0003639
Biological sample resources BioSample; SAMN03151938
Other Wikidata; Q54832168
Entry history
Entry creation04-Apr-2012
Last entry update23-Sep-2021
Version number20