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Cellosaurus HARA-B (CVCL_2915)

[Text version]
Cell line name HARA-B
Synonyms HARAB
Accession CVCL_2915
Resource Identification Initiative To cite this cell line use: HARA-B (RRID:CVCL_2915)
Comments Population: Japanese.
Characteristics: Produces high level of parathyroid hormone-related peptide (PTHrP).
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Val143Ala (c.428T>C); ClinVar=VCV000804214; Zygosity=Homozygous (from parent cell line).
Disease Lung squamous cell carcinoma (NCIt: C3493)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2914 (HARA [Human squamous cell lung carcinoma])
Children:
CVCL_A9FF (HARA-B-GFP)CVCL_4W91 (HARA-B4)
Sex of cell Male
Age at sampling 57Y
Category Cancer cell line
STR profile Source(s): CLS; JCRB

Markers:
AmelogeninX,Y
CSF1PO13
D2S133819,20
D3S135815
D5S81812
D6S104311,14
D7S82012
D8S117910,12
D12S39118,19
D13S3179
D16S53910
D18S5113
D19S43313
D21S1130
FGA20
Penta D9
Penta E11
TH017
TPOX8,9
vWA16,17

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Publications

PubMed=8752176
Iguchi H., Tanaka S., Ozawa Y., Kashiwakuma T., Kimura T., Hiraga T., Ozawa H., Kono A.
An experimental model of bone metastasis by human lung cancer cells: the role of parathyroid hormone-related protein in bone metastasis.
Cancer Res. 56:4040-4043(1996)

PubMed=11668474; DOI=10.1002/ijc.1425
Iguchi H., Onuma E., Sato K., Sato K., Ogata E.
Involvement of parathyroid hormone-related protein in experimental cachexia induced by a human lung cancer-derived cell line established from a bone metastasis specimen.
Int. J. Cancer 94:24-27(2001)

Cross-references
Cell line collections (Providers) CLS; 300465
JCRB; JCRB1080.1
JCRB; NIHS0352.1 - Discontinued
KCB; KCB 2016077YJ
Cell line databases/resources cancercelllines; CVCL_2915
CCRID; 5301HUM-KCB16077YJ
Encyclopedic resources Wikidata; Q54881314
Gene expression databases GEO; GSM1374488
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number21