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Cellosaurus HCS-2 (CVCL_2918)

[Text version]
Cell line name HCS-2
Synonyms HCS2
Accession CVCL_2918
Resource Identification Initiative To cite this cell line use: HCS-2 (RRID:CVCL_2918)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Doubling time: ~65 hours (Note=At 17th passage) (PubMed=2979208); ~39 hours (Note=Lot 09092016) (JCRB=JCRB1203).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
HLA typing Source: PubMed=9023415
Class I
HLA-AA*24:02
HLA-BB*52:01
HLA-CC*12:02
Disease Cervical squamous cell carcinoma, not otherwise specified (NCIt: C180839)
Squamous cell carcinoma of the cervix uteri (ORDO: Orphanet_213767)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 42Y
Category Cancer cell line
STR profile Source(s): DepMap; JCRB; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10
D2S133824
D3S135816,18
D5S81811,12
D7S82010,12
D8S117913,14
D13S31711
D16S5399,10
D18S5113,14
D19S43312,13
D21S1131.2
FGA23,24
Penta D11,13
Penta E5,21
TH016
TPOX9,11
vWA18

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Publications

PubMed=2979208
Morisawa T., Kuramoto H., Shimoda T., Sakamoto I., Kato Y., Hamano M.
Establishment and characterization of a new SCC antigen producing cell line (HCS-2) from a carcinoma of the uterine cervix.
Hum. Cell 1:308-314(1988)

PubMed=9023415; DOI=10.1006/cimm.1996.1062
Seki N., Hoshino T., Kikuchi M., Hayashi A., Itoh K.
HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer.
Cell. Immunol. 175:101-110(1997)

PubMed=25877200; DOI=10.1038/nature14397
Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

Cross-references
Cell line collections (Providers) JCRB; JCRB1203
JCRB; NIHS0405 - Discontinued
Cell line databases/resources cancercelllines; CVCL_2918
Cell_Model_Passport; SIDM01815
DepMap; ACH-001515
Biological sample resources BioSample; SAMN03470913
Encyclopedic resources Wikidata; Q54881899
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number18