Cellosaurus HEC-59 (CVCL_2930)

Cell line name HEC-59
Synonyms HEC59; Hec59
Accession CVCL_2930
Resource Identification Initiative To cite this cell line use: HEC-59 (RRID:CVCL_2930)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: MD Anderson Cell Lines Project.
Doubling time: 24.3 hours, at 152th passage (DOI=10.5795/jjscc.26.433).
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Endometrial adenocarcinoma (NCIt: C7359)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): AddexBio; JCRB; PubMed=25877200

Penta D9,10,11
Penta E15,16
TPOX11,14 (AddexBio; JCRB)
11 (PubMed=25877200)
Web pages http://tcpaportal.org/mclp/

Morisawa T.
The results of primary culture of endometrial adenocarcinoma and characterization of its established cell line.
Nihon Rinsho Saibo Gakkai Zasshi 26:433-442(1987)

PubMed=2064198; DOI=10.1111/j.1749-6632.1991.tb37884.x
Kuramoto H., Nishida M., Morisawa T., Hamano M., Hata H., Kato Y., Ohno E., Iida T.
Establishment and characterization of human endometrial cancer cell lines.
Ann. N. Y. Acad. Sci. 622:402-421(1991)

Hoang J.-M., Cottu P.H., Thuille B., Salmon R.J., Thomas G., Hamelin R.
BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines.
Cancer Res. 57:300-303(1997)

PubMed=12227503; DOI=10.1111/j.1749-0774.2002.tb00103.x
Kurarmoto H., Hamano M., Imai M.
HEC-1 cells.
Hum. Cell 15:81-95(2002)

Kuramoto H., Hamano M., Imai M., Fujisawa T., Kamata Y., Arai T., Kawaguchi M.
HEC-1 cells: establishment of an in vitro experimental system in endometrial carcinoma.
(In) Cell and molecular biology of endometrial carcinoma; Kuramoto H., Nishida M. (eds.); pp.3-34; Springer; Tokyo (2003)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P., Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cell line collections AddexBio; C0026001/42
JCRB; NIHS0392 - Discontinued
Cell line databases/resources CCLE; HEC59_ENDOMETRIUM
Biological sample resources BioSample; SAMN03472458
BioSample; SAMN03470882
Gene expression databases GEO; GSM887074
GEO; GSM888144
Polymorphism and mutation databases Cosmic; 1070806
Cosmic; 1223492
Cosmic; 1576460
Cosmic; 1622901
Cosmic; 1696750
Cosmic; 2030472