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Cellosaurus HL60RG (CVCL_2945)

[Text version]

Cell line name HL60RG
Synonyms HL60-RG
Accession CVCL_2945
Resource Identification Initiative To cite this cell line use: HL60RG (RRID:CVCL_2945)
Comments Doubling time: ~2 days (lot 12182006) (JCRB).
Derived from sampling site: Peripheral blood.
Sequence variations Gene deletion; HGNC; 11998; TP53; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0002 (HL-60)
Sex of cell Female
Age at sampling 35Y
Category Cancer cell line
STR profile Source(s): JCRB; PubMed=11416159

Markers:
AmelogeninX
CSF1PO13,14
D5S81812
D7S82011,12
D8S117912,13
D13S3178,11
D16S53911
D18S5114,15
D21S1130
FGA21,22,24
TH018
TPOX8,11
vWA16

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Publications

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

Cross-references
Cell line collections JCRB; JCRB0006
Cell line databases/resources LINCS_LDP; LCL-2056
Gene expression databases GEO; GSM254145
Other Wikidata; Q54889835
Polymorphism and mutation databases Progenetix; CVCL_2945
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number24