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Cellosaurus HUVEC-C (CVCL_2959)

[Text version]

Cell line name HUVEC-C
Synonyms HUV-EC-C; HUVEC
Accession CVCL_2959
Resource Identification Initiative To cite this cell line use: HUVEC-C (RRID:CVCL_2959)
Comments Characteristics: Life expectancy of 50 to 60 population doublings (ATCC). 54 PDL (PubMed=28755030).
Characteristics: Contains an integrated copy of HHV-6B (CI-HHV-6B) at the distal end of chromosome 9 (PubMed=28755030).
Doubling time: ~23.5 hours (between passages 18 and 30), ~67 hours (between passages 24 and 27), ~84 hours (between passages 27 and 30), ~100 hours (between passages 32 and 34) (PubMed=28755030).
Discontinued: IZSLER; BS CL 145; probable.
Derived from sampling site: Umbilical vein. Cell type=Endothelial cell.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_0F27 (HUVEC-CS)
Sex of cell Female
Age at sampling <1D
Category Finite cell line
STR profile Source(s): ATCC; JCRB; PubMed=28755030

Markers:
AmelogeninX
CSF1PO11,12
D3S135816
D5S81811,12
D7S8208,12
D8S117914,16
D13S3179,11
D16S53911,12
D18S5113,17
D21S1128,31
FGA21,23
Penta D12,13
Penta E7,13
TH016,9.3
TPOX8,11
vWA16

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Publications

PubMed=6333682; DOI=10.1073/pnas.81.20.6413
Hoshi H., McKeehan W.L.
Brain- and liver cell-derived factors are required for growth of human endothelial cells in serum-free culture.
Proc. Natl. Acad. Sci. U.S.A. 81:6413-6417(1984)

PubMed=28755030; DOI=10.1007/s10616-017-0119-y
Shioda S., Kasai F., Ozawa M., Hirayama N., Satoh M., Kameoka Y., Watanabe K., Shimizu N., Tang H.-M., Mori Y., Kohara A.
The human vascular endothelial cell line HUV-EC-C harbors the integrated HHV-6B genome which remains stable in long term culture.
Cytotechnology 70:141-152(2018)

PubMed=29892436; DOI=10.1098/rsos.172472
Shioda S., Kasai F., Watanabe K., Kawakami K., Ohtani A., Iemura M., Ozawa M., Arakawa A., Hirayama N., Kawaguchi E., Tano T., Miyata S., Satoh M., Shimizu N., Kohara A.
Screening for 15 pathogenic viruses in human cell lines registered at the JCRB Cell Bank: characterization of in vitro human cells by viral infection.
R. Soc. Open Sci. 5:172472-172472(2018)

Cross-references
Cell line collections ATCC; CRL-1730
CCTCC; GDC0166
IZSLER; BS CL 145
JCRB; IFO50271
KCB; KCB 200648YJ
KCB; KCB 2012087YJ
NCBI_Iran; C554
Cell line databases/resources CLO; CLO_0004307
CCRID; 4201HUM-CCTCC00635
Lonza; 1085
Anatomy/cell type resources BTO; BTO:0001949
Biological sample resources BioSample; SAMN01821567
BioSample; SAMN01821732
BioSample; SAMN03471415
Encyclopedic resources Wikidata; Q54896935
Entry history
Entry creation04-Apr-2012
Last entry update16-Dec-2021
Version number21