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Cellosaurus J-111 (CVCL_2965)

[Text version]

Cell line name J-111
Synonyms J 111; J111; JIII; Oregon J-111
Accession CVCL_2965
Resource Identification Initiative To cite this cell line use: J-111 (RRID:CVCL_2965)
Comments Group: Space-flown cell line (cellonaut).
Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=5641128; PubMed=566722; PubMed=1246601; PubMed=12592342; PubMed=20143388). Originally thought to originate from a 25 year old female patient with acute monocytic leukemia.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00009.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Anecdotal: Have been flown in space on the ISS to study motility and cytoskeletal structures (PubMed=21246756).
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): CCRID; JCRB; PubMed=11416159

Markers:
AmelogeninX
CSF1PO9,10
D3S135815,18
D5S81811,12
D7S8208,12
D8S117912
D13S31712,14 (CCRID)
12,13.3 (JCRB)
D16S5399,10
D18S5116
D21S1127,28
FGA18,21
Penta D8,15
Penta E7,17
TH017
TPOX8,12
vWA16,18

Run an STR similarity search on this cell line
Web pages http://www.cellresource.cn/fdetail.aspx?id=426
http://iclac.org/wp-content/uploads/Cross-Contaminations_v9_distribution.xlsx
Publications

PubMed=13260360
Osgood E.E., Brooke J.H.
Continuous tissue culture of leukocytes from human leukemic bloods by application of gradient principles.
Blood 10:1010-1022(1955)

PubMed=14185313; DOI=10.1126/science.146.3641.241
Cell Culture Collection Committee
Animal cell strains. The Cell Culture Collection Committee has assembled and certified 23 strains of animal cells.
Science 146:241-243(1964)

PubMed=5641128; DOI=10.1038/217750a0
Gartler S.M.
Apparent Hela cell contamination of human heteroploid cell lines.
Nature 217:750-751(1968)

PubMed=4894370; DOI=10.1002/1097-0142(196908)24:2<211::AID-CNCR2820240202>3.0.CO;2-3
Southam C.M., Burchenal J.H., Clarkson B.D., Tanzi A., Mackey R., McComb V.
Heterotransplantability of human cell lines derived from leukemia and lymphomas into immunologically tolerant rats.
Cancer 24:211-222(1969)

PubMed=1246601; DOI=10.1126/science.1246601
Nelson-Rees W.A., Flandermeyer R.R.
HeLa cultures defined.
Science 191:96-98(1976)

PubMed=566722; DOI=10.1007/BF02616110
Lavappa K.S.
Survey of ATCC stocks of human cell lines for HeLa contamination.
In Vitro 14:469-475(1978)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=9510473; DOI=10.1111/j.1349-7006.1998.tb00476.x
Hosoya N., Hangaishi A., Ogawa S., Miyagawa K., Mitani K., Yazaki Y., Hirai H.
Frameshift mutations of the hMSH6 gene in human leukemia cell lines.
Jpn. J. Cancer Res. 89:33-39(1998)

PubMed=12592342; DOI=10.1038/sj.leu.2402799
Drexler H.G., Dirks W.G., Matsuo Y., MacLeod R.A.F.
False leukemia-lymphoma cell lines: an update on over 500 cell lines.
Leukemia 17:416-426(2003)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=21246756; DOI=10.1002/cm.20499
Meloni M.A., Galleri G., Pani G., Saba A., Pippia P., Cogoli-Greuter M.
Space flight affects motility and cytoskeletal structures in human monocyte cell line J-111.
Cytoskeleton 68:125-137(2011)

Cross-references
Cell line collections ATCC; CCL-24 - Discontinued
ECACC; 93120824
IZSLER; BS TCL 30
JCRB; IFO50005
JCRB; JCRB0073
Cell line databases/resources CLDB; cl2915
CLDB; cl2916
CCRID; 3111C0002000000054
Ontologies CLO; CLO_0006981
CLO; CLO_0007024
Biological sample resources BioSample; SAMN03151724
Other Wikidata; Q54898403
Polymorphism and mutation databases Cosmic; 919124
Cosmic; 998751
Cosmic; 1037668
Entry history
Entry creation04-Apr-2012
Last entry updated24-May-2019
Version number19