Cellosaurus KHM-1B (CVCL_2972)

Cell line name KHM-1B
Synonyms KHM1B
Accession CVCL_2972
Resource Identification Initiative To cite this cell line use: KHM-1B (RRID:CVCL_2972)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Characteristics: Produces IgA lambda.
Doubling time: ~2 day (PubMed=2458153).
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Pleural effusion.
Disease Plasma cell myeloma (NCIt: C3242)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_9546 ! KHM-1A
Sex of cell Male
Category Cancer cell line
STR profile Source(s): JCRB; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10
D13S31711
D16S5399
D18S5116,18
D21S1130,31
D3S135815
D5S81811
D7S82010
D8S117911,12
FGA24
Penta D9,12
Penta E8,16
TH016
TPOX11
vWA14,17
Publications

PubMed=2458153
Matsuzaki H., Hata H., Takeya M., Takatsuki K.
Establishment and characterization of an amylase-producing human myeloma cell line.
Blood 72:978-982(1988)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Drexler H.G., Matsuo Y.
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

PubMed=18647998; DOI=10.1093/jncimonographs/lgn011
Dib A., Gabrea A., Glebov O.K., Bergsagel P.L., Kuehl W.M.
Characterization of MYC translocations in multiple myeloma cell lines.
J. Natl. Cancer Inst. Monogr. 39:25-31(2008)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

Cross-references
Cell line collections JCRB; JCRB0133
JCRB; NIHS0190 - Discontinued
Cell line databases/resources CCLE; KHM1B_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Ontologies EFO; EFO_0006609
Biological sample resources BioSample; SAMN03472941
Gene expression databases GEO; GSM887209
GEO; GSM888282
Polymorphism and mutation databases Cosmic; 2081389