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Cellosaurus HT168 (CVCL_2H38)

[Text version]

Cell line name HT168
Synonyms HT-168
Accession CVCL_2H38
Resource Identification Initiative To cite this cell line use: HT168 (RRID:CVCL_2H38)
Comments Population: Caucasian.
Characteristics: Low metastatic potential.
Sequence variations Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Val274Phe (c.820G>T); ClinVar=VCV000376674; Zygosity=Homozygous (from parent cell line).
Disease Amelanotic melanoma (NCIt: C3802)
Derived from metastatic site: Lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1059 (A2058)
Children:
CVCL_2H39 (HT168-M1)
Sex of cell Male
Age at sampling 43Y
Category Cancer cell line
Publications

PubMed=2203689; DOI=10.1002/ijc.2910460322
Ladanyi A., Timar J., Paku S., Molnar G., Lapis K.
Selection and characterization of human melanoma lines with different liver-colonizing capacity.
Int. J. Cancer 46:456-461(1990)

PubMed=11448059; DOI=10.1023/A:1011043412634
Adam Z., Adany R., Ladanyi A., Timar J., Balazs M.
Liver metastatic ability of human melanoma cell line is associated with losses of chromosomes 4, 9p21-pter and 10p.
Clin. Exp. Metastasis 18:295-302(2000)

Cross-references
Ontologies BTO; BTO:0005041
Other Wikidata; Q54896575
Entry history
Entry creation22-Sep-2015
Last entry update20-May-2021
Version number10