ID   HT168
AC   CVCL_2H38
SY   HT-168
DR   BTO; BTO:0005041
DR   cancercelllines; CVCL_2H38
DR   Wikidata; Q54896575
RX   PubMed=2203689;
RX   PubMed=11448059;
CC   Population: Caucasian.
CC   Characteristics: Low metastatic potential.
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Val274Phe (c.820G>T); ClinVar=VCV000376674; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
DI   NCIt; C3802; Amelanotic melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1059 ! A2058
SX   Male
AG   43Y
CA   Cancer cell line
DT   Created: 22-09-15; Last updated: 05-10-23; Version: 13
//
RX   PubMed=2203689; DOI=10.1002/ijc.2910460322;
RA   Ladanyi A., Timar J., Paku S., Molnar G., Lapis K.;
RT   "Selection and characterization of human melanoma lines with different
RT   liver-colonizing capacity.";
RL   Int. J. Cancer 46:456-461(1990).
//
RX   PubMed=11448059; DOI=10.1023/A:1011043412634;
RA   Adam Z., Adany R., Ladanyi A., Timar J., Balazs M.;
RT   "Liver metastatic ability of human melanoma cell line is associated
RT   with losses of chromosomes 4, 9p21-pter and 10p.";
RL   Clin. Exp. Metastasis 18:295-302(2000).
//