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Cellosaurus MCF-7/VD(R) (CVCL_2Z97)

[Text version]
Cell line name MCF-7/VD(R)
Accession CVCL_2Z97
Resource Identification Initiative To cite this cell line use: MCF-7/VD(R) (RRID:CVCL_2Z97)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:27300; Vitamin D.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=11500919; DOI=10.1002/jcb.1162
Hansen C.M., Rohde L., Madsen M.W., Hansen D., Colston K.W., Pirianov G., Holm P.K., Binderup L.
MCF-7/VD(R): a new vitamin D resistant cell line.
J. Cell. Biochem. 82:422-436(2001)

Cross-references
Cell line databases/resources cancercelllines; CVCL_2Z97
Encyclopedic resources Wikidata; Q54904397
Entry history
Entry creation22-Sep-2015
Last entry update05-Oct-2023
Version number14