Cellosaurus KYM-1 (CVCL_3007)

Cell line name KYM-1
Synonyms Kym-1
Accession CVCL_3007
Resource Identification Initiative To cite this cell line use: KYM-1 (RRID:CVCL_3007)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Alveolar rhabdomyosarcoma (NCIt: C3749)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children: CVCL_5616 (KYM-1D4)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; JCRB

Markers:
AmelogeninX
CSF1PO12
D13S3178
D16S5399,10
D5S81811,14
D7S82011
TH017,9
TPOX8,11
vWA17
Publications

PubMed=3830265
Sekiguchi M., Shiroko Y., Suzuki T., Imada M., Miyahara M., Fujii G.
Characterization of a human rhabdomyosarcoma cell strain in tissue culture.
Biomed. Pharmacother. 39:372-380(1985)

PubMed=1960402; DOI=10.1016/0022-1759(91)90239-C
Meager A.
A cytotoxicity assay for tumour necrosis factor using a human rhabdomyosarcoma cell line.
J. Immunol. Methods 144:141-143(1991)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=24418192; DOI=10.1111/cas.12352
Takita J., Chen Y., Kato M., Ohki K., Sato Y., Ohta S., Sugita K., Nishimura R., Hoshino N., Seki M., Sanada M., Oka A., Hayashi Y., Ogawa S.
Genome-wide approach to identify second gene targets for malignant rhabdoid tumors using high-density oligonucleotide microarrays.
Cancer Sci. 105:258-264(2014)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections JCRB; JCRB0627
Cell line databases/resources CCLE; KYM1_SOFT_TISSUE
Cosmic-CLP; 1240166
GDSC; 1240166
LINCS_LDP; LCL-1412
Biological sample resources BioSample; SAMN03471640
Gene expression databases GEO; GSM827283
GEO; GSM887245
GEO; GSM888320
GEO; GSM1670015
Polymorphism and mutation databases Cosmic; 801759
Cosmic; 1995475
Cosmic; 2144781