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Cellosaurus Lu-65A (CVCL_3012)

[Text version]

Cell line name Lu-65A
Synonyms LU-65A; LU65A
Accession CVCL_3012
Resource Identification Initiative To cite this cell line use: Lu-65A (RRID:CVCL_3012)
Comments Population: Japanese.
Omics: SNP array analysis.
Misspelling: LC-95A; In PubMed=9023415.
Derived from sampling site: Lung.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9884; RB1; Simple; p.Ser82Ter (c.245C>A); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Glu11Gln (c.31G>C); ClinVar=VCV000041723; Zygosity=Homozygous (from parent cell line).
HLA typing Source: PubMed=9023415
Class I
HLA-AA*11:01,24:02
HLA-BB*40:02
HLA-CC*03:04
Disease Lung giant cell carcinoma (NCIt: C4452)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1392 (Lu-65)
Sex of cell Male
Age at sampling 64Y
Category Cancer cell line
STR profile Source(s): JCRB

Markers:
AmelogeninX
CSF1PO13
D5S81812
D7S82011,12
D13S31710
D16S5399,11
TH016
TPOX8,11
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=9023415; DOI=10.1006/cimm.1996.1062
Seki N., Hoshino T., Kikuchi M., Hayashi A., Itoh K.
HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer.
Cell. Immunol. 175:101-110(1997)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cross-references
Cell line collections JCRB; JCRB0054
Cell line databases/resources LINCS_LDP; LCL-1905
Biological sample resources BioSample; SAMN03472811
Encyclopedic resources Wikidata; Q54903207
Gene expression databases GEO; GSM827386
Polymorphism and mutation databases Cosmic; 753590
Cosmic; 1001659
Progenetix; CVCL_3012
Entry history
Entry creation04-Apr-2012
Last entry update23-Sep-2021
Version number22