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Cellosaurus 184A1 (CVCL_3040)

[Text version]

Cell line name 184A1
Synonyms H184A1
Accession CVCL_3040
Secondary accession CVCL_8222
Resource Identification Initiative To cite this cell line use: 184A1 (RRID:CVCL_3040)
Comments Part of: MD Anderson Cell Lines Project.
Microsatellite instability: Stable (MSS) (PubMed=12661003).
Transformant: ChEBI; CHEBI:29865; Benzo[a]pyrene.
Omics: CNV analysis.
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
HLA typing Source: PubMed=25960936
Class I
HLA-AA*02:01,02:01
HLA-BB*18:01,18:01
HLA-CC*07:01,07:01
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_K049 (184)
Children:
CVCL_9665 (184A1N4)
Sex of cell Female
Age at sampling 21Y
Category Transformed cell line
STR profile Source(s): ATCC; PubMed=28889351

Markers:
AmelogeninX
CSF1PO10,11
D5S81811,13
D7S8209,11
D13S31711
D16S53911,12
D21S1129,30
TH019.3
TPOX11
vWA18,19

Run an STR similarity search on this cell line
Web pages http://hmec.lbl.gov/mreview.htm
http://tcpaportal.org/mclp/
Publications

PubMed=3857588; DOI=10.1073/pnas.82.8.2394
Stampfer M.R., Bartley J.C.
Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene.
Proc. Natl. Acad. Sci. U.S.A. 82:2394-2398(1985)

Patent=US4808532
Stampfer M.R.
Continuous human cell lines and method of making same.
Patent number US4808532, 28-Feb-1989

PubMed=2702624; DOI=10.1016/0165-4608(89)90056-3
Walen K.H., Stampfer M.R.
Chromosome analyses of human mammary epithelial cells at stages of chemical-induced transformation progression to immortality.
Cancer Genet. Cytogenet. 37:249-261(1989)

DOI=10.1007/978-1-4612-0411-4_26
Stampfer M.R., Yaswen P., Parry G., Hosoda J.
An in vitro human mammary epithelial model system for studies of differentiation and carcinogenesis.
(In) Neoplastic transformation in human cell system. Mechanism of carcinogenesis; Rhim J.S., Dritschilo A. (eds.); pp.259-267; Humana Press; New York (1990)

PubMed=8504475; DOI=10.1093/carcin/14.5.833
Lehman T.A., Modali R., Boukamp P., Stanek J., Bennett W.P., Welsh J.A., Metcalf R.A., Stampfer M.R., Fusenig N., Rogan E.M., Harris C.C.
p53 mutations in human immortalized epithelial cell lines.
Carcinogenesis 14:833-839(1993)

PubMed=9671407; DOI=10.1038/sj.onc.1201814
Sweeney K.J., Swarbrick A., Sutherland R.L., Musgrove E.A.
Lack of relationship between CDK activity and G1 cyclin expression in breast cancer cells.
Oncogene 16:2865-2878(1998)

PubMed=12661003; DOI=10.1002/gcc.10196
Seitz S., Wassmuth P., Plaschke J., Schackert H.K., Karsten U., Santibanez-Koref M.-F., Schlag P.M., Scherneck S.
Identification of microsatellite instability and mismatch repair gene mutations in breast cancer cell lines.
Genes Chromosomes Cancer 37:29-35(2003)

PubMed=19582160; DOI=10.1371/journal.pone.0006146
Kao J., Salari K., Bocanegra M., Choi Y.-L., Girard L., Gandhi J., Kwei K.A., Hernandez-Boussard T., Wang P., Gazdar A.F., Minna J.D., Pollack J.R.
Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery.
PLoS ONE 4:E6146-E6146(2009)

PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110
Daemen A., Griffith O.L., Heiser L.M., Wang N.J., Enache O.M., Sanborn Z., Pepin F., Durinck S., Korkola J.E., Griffith M., Hur J.S., Huh N., Chung J., Cope L., Fackler M.J., Umbricht C., Sukumar S., Seth P., Sukhatme V.P., Jakkula L.R., Lu Y., Mills G.B., Cho R.J., Collisson E.A., van't Veer L.J., Spellman P.T., Gray J.W.
Modeling precision treatment of breast cancer.
Genome Biol. 14:R110.1-R110.14(2013)

PubMed=25960936; DOI=10.4161/21624011.2014.954893
Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:E954893-E954893(2014)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P., Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=28889351; DOI=10.1007/s10549-017-4496-x
Saunus J.M., Smart C.E., Kutasovic J.R., Johnston R.L., Kalita-de Croft P., Miranda M., Rozali E.N., Vargas A.C., Reid L.E., Lorsy E., Cocciardi S., Seidens T., McCart Reed A.E., Dalley A.J., Wockner L.F., Johnson J., Sarkar D., Askarian-Amiri M.E., Simpson P.T., Khanna K.K., Chenevix-Trench G., Al-Ejeh F., Lakhani S.R.
Multidimensional phenotyping of breast cancer cell lines to guide preclinical research.
Breast Cancer Res. Treat. 167:289-301(2018)

Cross-references
Cell line collections ATCC; CRL-8798
IZSLER; BS CL 178
Cell line databases/resources LINCS_HMS; 51088
LINCS_LDP; LCL-2080
Ontologies CLO; CLO_0001137
Biological sample resources BioSample; SAMN03471210
Gene expression databases GEO; GSM350522
GEO; GSM845393
GEO; GSM843436
GEO; GSM1172932
GEO; GSM1172844
Other Wikidata; Q54582476