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Cellosaurus NB(TU)1 (CVCL_3041)

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Cell line name NB(TU)1
Synonyms NBTU1; NB(TU)1-10; NB (TU) 1-10; NB-TU-1-10; NBTU110
Accession CVCL_3041
Resource Identification Initiative To cite this cell line use: NB(TU)1 (RRID:CVCL_3041)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Doubling time: 49 hours (PubMed=9378542).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.86
Native American0.24
East Asian, North77.99
East Asian, South19.62
South Asian1.28
European, North0
European, South0
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 1Y8M
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; JCRB; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10,12
D2S133817,19
D3S135815
D5S81810
D7S82012
D8S117913,16
D13S31712
D16S5399,11,12 (Cosmic-CLP)
9,12 (JCRB)
9,11 (PubMed=25877200)
D18S5113,15
D19S43313.2,14
D21S1130
FGA22,24
Penta D12,14
Penta E14,19
TH019
TPOX11
vWA14

Run an STR similarity search on this cell line
Publications

PubMed=9378542; DOI=10.1002/(SICI)1097-0215(19970917)72:6<1070::AID-IJC23>3.0.CO;2-7
Inoue A., Yokomori K., Tanabe H., Mizusawa H., Sofuni T., Hayashi Y., Tsuchida Y., Shimatake H.
Extensive genetic heterogeneity in the neuroblastoma cell line NB(TU)1.
Int. J. Cancer 72:1070-1077(1997)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections JCRB; JCRB0154
JCRB; NIHS0179 - Discontinued
Cell line databases/resources CCLE; NBTU110_AUTONOMIC_GANGLIA
Cell_Model_Passport; SIDM00579
Cosmic-CLP; 1240181
DepMap; ACH-002277
LINCS_LDP; LCL-1976
Biological sample resources BioSample; SAMN03470814
BioSample; SAMN03470968
Chemistry resources GDSC; 1240181
PharmacoDB; NBTU110_982_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM827250
GEO; GSM1670144
Other Wikidata; Q54907513
Polymorphism and mutation databases Cosmic; 1037354
Cosmic; 2131596
Entry history
Entry creation04-Apr-2012
Last entry updated12-Mar-20
Version number23