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Cellosaurus NCO2 (CVCL_3043)

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Cell line name NCO2
Synonyms NC02; NCO-2
Accession CVCL_3043
Resource Identification Initiative To cite this cell line use: NCO2 (RRID:CVCL_3043)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: 1.2 days (lot 01132005) (JCRB).
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Peripheral blood.
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 35Y
Category Cancer cell line
STR profile Source(s): JCRB


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Ogura M., Morishima Y., Ohno R., Saito H., Kalo K.
Establishment and characterization of a new human myeloid cell line with positive masked Ph1 chromosome and myeloperoxidase from CML in myeloid blastic crisis.
Jpn. J. Cancer Res. 76:597a-597a(1985)

Morishita Y., Kataoka T., Towatari M., Ito T., Inoue H., Ogura M., Morishima Y., Saito H.
Up-regulation of transferrin receptor gene expression by granulocyte colony-stimulating factor in human myeloid leukemia cells.
Cancer Res. 50:7955-7961(1990)

PubMed=9738977; DOI=10.1111/j.1349-7006.1998.tb03275.x
Takizawa J., Suzuki R., Kuroda H., Utsunomiya A., Kagami Y., Joh T., Aizawa Y., Ueda R., Seto M.
Expression of the TCL1 gene at 14q32 in B-cell malignancies but not in adult T-cell leukemia.
Jpn. J. Cancer Res. 89:712-718(1998)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

Cell line collections JCRB; IFO50525
Biological sample resources BioSample; SAMN03472804
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887454
GEO; GSM888534
Other Wikidata; Q54908244
Polymorphism and mutation databases Cosmic; 2009520