ID   NCC-StC-K140
AC   CVCL_3055
SY   NCCStCK140; NCCSTCK140; K140
DR   CLO; CLO_0050803
DR   ArrayExpress; E-MTAB-2770
DR   BioSample; SAMN03472022
DR   BioSample; SAMN03472448
DR   BioSample; SAMN10988058
DR   CCLE; NCCSTCK140_STOMACH
DR   DepMap; ACH-000110
DR   GEO; GSM888427
DR   IARC_TP53; 28306
DR   JCRB; JCRB1228
DR   LiGeA; CCLE_272
DR   PharmacoDB; NCCStCK140_996_2019
DR   Progenetix; CVCL_3055
DR   RCB; RCB2224
DR   Wikidata; Q54907635
RX   PubMed=8263010;
RX   PubMed=22460905;
RX   PubMed=30894373;
RX   PubMed=31068700;
CC   Part of: Cancer Cell Line Encyclopedia (CCLE) project.
CC   Population: Japanese.
CC   Doubling time: ~44 hours (lot 03222018) (JCRB).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (CCLE).
CC   Omics: Deep exome analysis.
CC   Omics: Deep RNAseq analysis.
CC   Omics: SNP array analysis.
CC   Genome ancestry: African=1.19%; Native American=0%; East Asian, North=80.7%; East Asian, South=13.81%; South Asian=0%; European, North=0%; European, South=4.29% (PubMed=30894373).
CC   Derived from sampling site: Stomach.
ST   Source(s): JCRB; RCB
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 12
ST   D16S539: 12
ST   D5S818: 9
ST   D7S820: 11,12 (JCRB)
ST   D7S820: 12 (RCB)
ST   TH01: 7,9
ST   TPOX: 8,11
ST   vWA: 14
DI   NCIt; C4911; Gastric carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Female
AG   36Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 23-09-21; Version: 16
//
RX   PubMed=8263010; DOI=10.1007/BF01202193;
RA   Inomata M., Kaneko A., Saijo N., Tokura S.;
RT   "Culture of retinoblastoma cells from clinical specimens:
RT   growth-promoting effect of 2-mercaptoethanol.";
RL   J. Cancer Res. Clin. Oncol. 120:149-155(1994).
//
RX   PubMed=22460905; DOI=10.1038/nature11003;
RA   Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A.,
RA   Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A.,
RA   Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J.,
RA   Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E.,
RA   Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J.,
RA   Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C.,
RA   Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C.,
RA   Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P.,
RA   Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L.,
RA   Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R.,
RA   Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.;
RT   "The Cancer Cell Line Encyclopedia enables predictive modelling of
RT   anticancer drug sensitivity.";
RL   Nature 483:603-607(2012).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3;
RA   Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C.,
RA   McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H.,
RA   Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F.,
RA   Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R.,
RA   Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C.,
RA   Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A.,
RA   Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D.,
RA   Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L.,
RA   Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A.,
RA   Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D.,
RA   Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M.,
RA   Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R.,
RA   Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A.,
RA   Sellers W.R.;
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//