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Cellosaurus NCI-H69VCR/R (CVCL_3058)

[Text version]
Cell line name NCI-H69VCR/R
Accession CVCL_3058
Resource Identification Initiative To cite this cell line use: NCI-H69VCR/R (RRID:CVCL_3058)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:28445; Vincristine (VCR).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Gly106_Arg108del (c.317_325delGGCAACCGT); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9884; RB1; Simple; p.Glu748Ter (c.2242G>T); ClinVar=VCV000013078; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Glu171Ter (c.511G>T); ClinVar=VCV000634771; Zygosity=Homozygous (from parent cell line).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1579 (NCI-H69)
Sex of cell Male
Age at sampling 55Y
Category Cancer cell line
STR profile Source(s): ECACC

Markers:
AmelogeninX
CSF1PO12
D5S81811
D7S8209
D13S31712
D16S53911
TH018,9
TPOX10
vWA16,17

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Cross-references
Cell line collections (Providers) ECACC; 96042330
Cell line databases/resources cancercelllines; CVCL_3058
Encyclopedic resources Wikidata; Q54908108
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number20