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Cellosaurus Onda 11 (CVCL_3076)

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Cell line name Onda 11
Synonyms no.11; no-11; NO11; Case 3
Accession CVCL_3076
Resource Identification Initiative To cite this cell line use: Onda 11 (RRID:CVCL_3076)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Population: Japanese.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Brain; right parietal lobe.
Sequence variations PTEN p.Gln17del (c.49_51delCAA) (PubMed=10551321).
TP53 p.Gly245Ser (c.733G>A) (ClinVar=VCV000012365) (PubMed=8878451).
Genome ancestry Source: PubMed=30894373

Origin% genome
Native American1.06
East Asian, North76.42
East Asian, South17.02
South Asian0
European, North1.56
European, South2.21
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 64Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DepMap; JCRB

D7S82011 (Cosmic-CLP; JCRB)
11,12 (DepMap)
Penta D12,13
Penta E13

Run an STR similarity search on this cell line

PubMed=3188836; DOI=10.1007/BF00686381
Onda K., Tanaka R., Washiyama K., Takeda N., Kumanishi T.
Correlation of DNA ploidy and morphological features of human glioma cell cultures with the establishment of cell lines.
Acta Neuropathol. 76:433-440(1988)

Onda K., Washiyama K., Tanaka R., Nishiyama A., Usui H., Kumanishi T.
GFAP-positive human glioma cell lines: no.11, no.10.
Hum. Cell 3:251-252(1990)

PubMed=8878451; DOI=10.1111/j.1349-7006.1996.tb02118.x
Zhang S., Endo S., Koga H., Ichikawa T., Feng X., Onda K., Washiyama K., Kumanishi T.
A comparative study of glioma cell lines for p16, p15, p53 and p21 gene alterations.
Jpn. J. Cancer Res. 87:900-907(1996)

PubMed=10551321; DOI=10.1111/j.1349-7006.1999.tb00838.x
Zhang S.J., Endo S., Ichikawa T., Yoshimura J., Onda K., Tanaka R., Washiyama K., Kumanishi T.
Rare-type mutations of MMAC1 tumor suppressor gene in human glioma cell lines and their tumors of origin.
Jpn. J. Cancer Res. 90:934-941(1999)

PubMed=16232199; DOI=10.1111/j.1349-7006.2005.00099.x
Saigusa K., Hashimoto N., Tsuda H., Yokoi S., Maruno M., Yoshimine T., Aoyagi M., Ohno K., Imoto I., Inazawa J.
Overexpressed Skp2 within 5p amplification detected by array-based comparative genomic hybridization is associated with poor prognosis of glioblastomas.
Cancer Sci. 96:676-683(2005)

PubMed=18415661; DOI=10.1007/s10014-007-0226-0
Tanaka Y., Zhang S.J., Terasaki H., Koga H., Endo S., Usui H., Washiyama K., Kumanishi T., Uematsu Y., Itakura T.
Frequent and variable abnormalities in p14 tumor suppressor gene in glioma cell lines.
Brain Tumor Pathol. 25:9-17(2008)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cell line collections JCRB; IFO50369
RCB; RCB4500
Cell line databases/resources CCLE; NO11_CENTRAL_NERVOUS_SYSTEM
Cell_Model_Passport; SIDM00573
CGH-DB; 152-1
Cosmic-CLP; 908450
DepMap; ACH-001606
Biological sample resources BioSample; SAMN03481112
Chemistry resources ChEMBL-Cells; CHEMBL3308224
ChEMBL-Targets; CHEMBL2366326
GDSC; 908450
PharmacoDB; no11_1164_2019
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM1670282
Other Wikidata; Q54936401
Polymorphism and mutation databases Cosmic; 687580
Cosmic; 908450
Cosmic; 2367542
IARC_TP53; 21592
IARC_TP53; 23806
Entry history
Entry creation04-Apr-2012
Last entry update12-Jan-2021
Version number29